Murphy's Luck may refer to:

• "Murphy's Luck", an episode from the television series Charmed
• An alternate term for the phrase Murphy's Law

• Luigi Bassi (clarinetist)
• Luigi Beltrame Quattrocchi
• Luigi Beltrame Quattrocchi and Maria Corsini
• Luigi Benoit
• Luigi Bodio
• Luigi bodio
• Luigi Bolis
• Luigi Bonardi
• Luigi Bonos
• Luigi Borrelli
• Luigi Bosatra
• Luigi Bosco
• Luigi Broglio
• Luigi Busdon
• Luigi Busidoni
• Luigibussolino
• Luigi Cadorna-class cruiser
• Luigi Caetani
• Luigi Calabresi
• Luigi Canonica
• Luigi Cantone
• Luigi Caponaro
• Luigi Capotosti
• Luigi Cappanera
• Luigi Capuano