| 词条 | NCI-Nature Pathway Interaction Database |
| 释义 |
|title = PID |logo = |description = Pathway Interaction Database. |scope = |organism = |center = |laboratory =National Cancer Institute NIH Nature Publishing Group |author = |citation = Schaefer & al. (2009)[1] |released = 2005 |standard =BioPAX |format = XML |url = http://pid.nci.nih.gov |download = |webservice = |sql = |sparql = |webapp = |standalone = |license = |versioning = |frequency = |curation = |bookmark = |version= }} The Pathway Interaction Database (PID) is a free biomedical database of human cellular signaling pathways.[1] The database contains information about the molecular interactions and reactions that take place in cells, with a particular focus on processes that might be relevant to cancer research and treatment. The database was established as collaboration between the U.S. National Cancer Institute, NIH and Nature Publishing Group in 2005 and was launched in November 2006. In September 2012, active curation was stopped but the data will be available for one year after that date. Database contentAs of November 2007, the database contained 59 pathways (comprising 3309 molecular interactions) curated by the NCI-Nature editorial team. New pathways are added each month. The database also contains 254 pathways (comprising 3003 interactions) imported from the June 2004 edition of the BioCarta pathway database. The NCI-Nature curated data is gathered from published research literature and reviewed by expert scientists before publication. Evidence codes are assigned to each molecular interaction, which allows users to evaluate the reliability of the interactions or to search for interactions identified by particular experimental techniques. Data output and downloadThe database content can be viewed in self-contained, pre-defined pathways. The database can also dynamically generate interaction networks to visualize the results of database searches. Pathways and dynamically generated networks are displayed in GIF and SVG images and can be downloaded as XML (including the standard pathway interchange format, BioPAX). The entire database is also available for download. See also
References1. ^1 {{cite journal |last=Schaefer|first=Carl F|authorlink=|author2=Anthony Kira |author3=Krupa Shiva |author4=Buchoff Jeffrey |author5=Day Matthew |author6=Hannay Timo |author7=Buetow Kenneth H |date=Jan 2009|title=PID: the Pathway Interaction Database|journal = Nucleic Acids Res.|volume=37|issue=Database issue|pages=D674-9|publisher= |location = England| issn = | pmid = 18832364|doi = 10.1093/nar/gkn653| bibcode = | oclc =| id = | url = | pmc = 2686461 | format = | accessdate = | laysummary = | laysource = | laydate = | quote = }} Other references
External links
2 : Biological databases|Systems biology |
| 随便看 |
|
开放百科全书收录14589846条英语、德语、日语等多语种百科知识，基本涵盖了大多数领域的百科知识，是一部内容自由、开放的电子版国际百科全书。