词条 | Necopidem |
释义 |
| verifiedrevid = 447997301 | IUPAC_name = N-([2-(4-ethylphenyl)-6-methylimidazo[1,2-a]pyridin-3-yl]methyl)-N,3-dimethylbutanamide | image = Necopidem.svg | width = 222 | tradename = | pregnancy_AU = | pregnancy_US = | pregnancy_category = | legal_AU = | legal_CA = | legal_UK = | legal_US = | legal_status = | routes_of_administration = | bioavailability = | protein_bound = | metabolism = | elimination_half-life = | excretion = | CAS_number_Ref = {{cascite|correct|??}} | CAS_number = 103844-77-5 | ATC_prefix = none | ATC_suffix = | PubChem = 3047786 | DrugBank_Ref = {{drugbankcite|correct|drugbank}} | DrugBank = | ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} | ChemSpiderID = 2310104 | UNII_Ref = {{fdacite|correct|FDA}} | UNII = G4N2F166MN | C=23 | H=29 | N=3 | O=1 | molecular_weight = 341.835 g/mol | smiles = O=C(N(C)Cc1c(nc2ccc(cn12)C)c3ccc(cc3)CC)CC(C)C | StdInChI_Ref = {{stdinchicite|correct|chemspider}} | StdInChI = 1S/C23H29N3O/c1-6-18-8-10-19(11-9-18)23-20(15-25(5)22(27)13-16(2)3)26-14-17(4)7-12-21(26)24-23/h7-12,14,16H,6,13,15H2,1-5H3 | StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} | StdInChIKey = YRMLUAGKHYADKJ-UHFFFAOYSA-N }}Necopidem is a drug in the imidazopyridine family, which is related to the better known drugs zolpidem and alpidem. It is therefore considered a nonbenzodiazepine and as such may have sedative and anxiolytic effects, given its structural similarity to other nonbenzodiazepine hypnotics.[1] References1. ^{{cite journal |title=Ethyl 8-(4-nitrophenyl)imidazo[1,2-a]pyridine-7-carboxylate |date=2010-12-01 |pmc=3011613 |journal=Acta Crystallographica Section E |volume=66 |number=12 |last1=Duan |first1=Gui-Yun |last2=Zhang |first2=Yu-Juan |last3=Hao |first3=Ben-Qian |pmid=21589555 |doi=10.1107/S1600536810047938 |pages=o3272}} {{Hypnotics and sedatives}}{{GABAAR PAMs}}{{sedative-stub}} 4 : Carboxamides|GABAA receptor positive allosteric modulators|Imidazopyridines|Sedatives |
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