| 词条 | Neomycin/polymyxin B/hydrocortisone |
| 释义 |
| drug_name = | type = combo | component1 = Neomycin | class1 = Antibiotic | component2 = Polymyxin B | class2 = Antibiotic | component3 = Hydrocortisone | class3 = Glucocorticoid | pronounce = | tradename = Cortisporin, others | Drugs.com = | MedlinePlus = | pregnancy_AU = | pregnancy_US = | pregnancy_category= | legal_AU = | legal_AU_comment = | legal_BR = | legal_BR_comment = | legal_CA = | legal_UK = | legal_US = Rx-only | legal_UN = | legal_NZ = | legal_status = | routes_of_administration = | CAS_number = | ATCvet = | ATC_prefix = | ATC_suffix = | PubChem = | DrugBank = }} Neomycin/polymyxin B/hydrocortisone, sold under the brand Cortisporin among others, is a medication consisting of neomycin, polymyxin B and hydrocortisone. It is a combination antibiotic and cortisone-like medicine. It can be used to treat infections of the ear canal and to help provide relief from redness, irritation, and discomfort of certain ear problems, including so-called swimmer's ear. In 2016, the drug came under scrutiny when Los Angeles Times columnist David Lazarus highlighted it as an example of unwarranted drug price markups by pharmaceutical companies.[1] The drug is owned by Dublin, Ireland-based Endo International. In 2016 it was the 290th most prescribed medication in the United States with more than a million prescriptions.[2] HistoryCortisporin was developed by Glaxo Wellcome and was approved by the Food and Drug Administration in 1975. In 1997, the rights were sold to Monarch Pharmaceuticals, a division of King Pharmaceuticals. In 2007, King sold it to JHP Pharmaceuticals. Par Pharmaceutical acquired JHP in 2014. In 2015, Endo International purchased Par.[1] CostIn David Lazarus' February 4, 2016 LA Times column, a pharmacist recalled a 10 milliliter vial of the drug selling for around $10 in the early 2010s. In 2015, the price was $100, and in 2016, it reportedly was selling for $195. A generic version, which is thinner and reportedly doesn't work as well, is priced at $144.[1] FormulationsGeneric name: neomycin sulfate, polymyxin B sulfate, and hydrocortisone Dosage form: otic suspension (liquid with ear dropper) Generic name: neomycin sulfate, polymyxin B sulfate, bacitracin zinc and hydrocortisone Dosage form: Dermatological ointment, drops References1. ^1 2 {{cite web|url=http://www.latimes.com/business/la-fi-lazarus-shkreli-20160204-column.html |title=Martin Shkreli isn't alone in ripping off patients with crazy drug prices |publisher=latimes.com |first=David|last=Lazarus|date=2016-02-04 |accessdate=2016-02-05}} 2. ^{{cite web |title=The Top 300 of 2019 |url=https://clincalc.com/DrugStats/Top300Drugs.aspx |website=clincalc.com |accessdate=22 December 2018}} External links
2 : Glucocorticoids|Combination drugs |
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