| 词条 | Neuromedin N |
| 释义 |
| Watchedfields = changed | verifiedrevid = 434792508 | ImageFile=Neuromedin N.svg | ImageSize= | IUPACName= | OtherNames= | Reference=[1] |Section1={{Chembox Identifiers | CASNo_Ref = {{cascite|correct|??}} | CASNo=102577-25-3 | PubChem = 9940301 | ChemSpiderID = 8115921 | IUPHAR_ligand = 1578 | SMILES=OC([C@H](CC(C)C)NC([C@@]([C@H](CC)C)([H])NC([C@H](CC1=CC=C(O)C=C1)NC([C@@H]2CCCN2C([C@](NC([C@@H](N)CCCCN)=O)([H])[C@H](CC)C)=O)=O)=O)=O)=O | StdInChI = 1S/C38H63N7O8/c1-7-23(5)31(36(50)42-29(38(52)53)20-22(3)4)43-34(48)28(21-25-14-16-26(46)17-15-25)41-35(49)30-13-11-19-45(30)37(51)32(24(6)8-2)44-33(47)27(40)12-9-10-18-39/h14-17,22-24,27-32,46H,7-13,18-21,39-40H2,1-6H3,(H,41,49)(H,42,50)(H,43,48)(H,44,47)(H,52,53)/t23-,24-,27-,28-,29-,30-,31-,32-/m0/s1 | StdInChIKey = RZMLVIHXZGQADB-YLUGYNJDSA-N |Section2={{Chembox Properties | Formula=C38H63N7O8 | MolarMass=745.949 | Appearance= | Density= | MeltingPt= | BoilingPt= | Solubility= |Section3={{Chembox Hazards | MainHazards= | FlashPt= | AutoignitionPt = }}{{infobox protein | Name = Neuromedin N | caption = | image = | width = | HGNCid = 8038 | Symbol = NN | AltSymbols = | EntrezGene = 4922 | OMIM = | RefSeq = | UniProt = | PDB = | ECnumber = | Chromosome = 12 | Arm = q | Band = 21 | LocusSupplementaryData = }}Neuromedin N is a neuropeptide derived from the same precursor polypeptide as neurotensin, and with similar but subtly distinct expression and effects.[2][3][4][5][6][7] References1. ^[https://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=3025353 Neuromedin N - Compound Summary], PubChem. {{Neuropeptides}}{{Neuropeptidergics}}{{biochem-stub}}2. ^{{cite journal |vauthors=Carraway RE, Mitra SP, Spaulding G |title=Posttranslational processing of the neurotensin/neuromedin-N precursor |journal=Annals of the New York Academy of Sciences |volume=668 |issue= 1 The Neurobiol|pages=1–16 |year=1992 |pmid=1463268 |doi= 10.1111/j.1749-6632.1992.tb27335.x|url=}} 3. ^{{cite journal |vauthors=Kitabgi P, De Nadai F, Rovère C, Bidard JN |title=Biosynthesis, maturation, release, and degradation of neurotensin and neuromedin N |journal=Annals of the New York Academy of Sciences |volume=668 |issue= 1 The Neurobiol|pages=30–42 |year=1992 |pmid=1463273 |doi= 10.1111/j.1749-6632.1992.tb27337.x|url=}} 4. ^{{cite journal |author=Vincent JP |title=Neurotensin receptors: binding properties, transduction pathways, and structure |journal=Cellular and Molecular Neurobiology |volume=15 |issue=5 |pages=501–12 |date=October 1995 |pmid=8719037 |doi= 10.1007/BF02071313|url=}} 5. ^{{cite journal |vauthors=Adams DH, Hanson GR, Keefe KA |title=Differential effects of cocaine and methamphetamine on neurotensin/neuromedin N and preprotachykinin messenger RNA expression in unique regions of the striatum |journal=Neuroscience |volume=102 |issue=4 |pages=843–51 |year=2001 |pmid=11182247 |doi= 10.1016/S0306-4522(00)00530-3|url=}} 6. ^{{cite journal |vauthors=Friry C, Feliciangeli S, Richard F, Kitabgi P, Rovere C |title=Production of recombinant large proneurotensin/neuromedin N-derived peptides and characterization of their binding and biological activity |journal=Biochemical and Biophysical Research Communications |volume=290 |issue=4 |pages=1161–8 |date=February 2002 |pmid=11811984 |doi=10.1006/bbrc.2001.6308 |url=}} 7. ^{{cite journal |author=Kitabgi P |title=Differential processing of pro-neurotensin/neuromedin N and relationship to pro-hormone convertases |journal=Peptides |volume=27 |issue=10 |pages=2508–14 |date=October 2006 |pmid=16904237 |doi=10.1016/j.peptides.2006.03.038 |url=}} 1 : Neuropeptides |
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