Nicholas Owen may refer to:

• Nicholas Owen (Jesuit) (c.1562–1606), one of the Forty Martyrs of England and Wales
• Nicholas Owen (priest) (1752–1811), Welsh Anglican priest and antiquarian
• Nicholas Owen (journalist) (born 1947), BBC news presenter
• Nick Owen (born 1947), presenter for Midlands Today
• Nicholas Bond-Owen (born 1968), child actor of the 1970s and 80s

• 350P/McNaught
• 350th Prakash Parv
• 350th Rifle Division
• 350th Rifle Division (Soviet Union)
• 350 (year)
• 3 511
• 3,511
• 35137 Meudon
• 351785 Reguly
• 351 AD
• 351P/Wiegert-PANSTARRS
• 351P/Wiegert–PANSTARRS
• 351st Division (Imperial Japanese Army)
• 351st Infantry Regiment (United States)
• 351st Rifle Division (Soviet Union)
• 351 U.S. 470
• 351 U.S. 570
• 351 (year)
• 352087 Aircraftman Ross
• 352148 Tarcisiozani
• 352333 Sylvievauclair
• 35239 Ottoseydl
• 3525th Pilot Training Wing
• 352646 Blumbahs
• 35265 Takeosaitou