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Nicomedes may refer to: - Nicomedes (mathematician), ancient Greek mathematician who discovered the conchoid
- Nicomedes, uncle of the 19th Agiad Spartan king Pleistoanax, commanded the Spartan army at the Battle of Tanagra
- Saint Nicomedes, Martyr of unknown era, whose feast is observed 15 September
Four kings of Bithynia in Anatolia, 3rd–1st century BC: - Nicomedes I of Bithynia, ruled 278–255 BC
- Nicomedes II of Bithynia, 149–127 BC
- Nicomedes III of Bithynia, 127–94 BC
- Nicomedes IV of Bithynia, 94–74 BC
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