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词条 Nitrofuran
释义

  1. References

  2. External links

Nitrofurans are a class of drugs typically used as antibiotics or antimicrobials.[1] The defining structural component is a furan ring with a nitro group.[2]

Members of this class of drugs include:

  • Antibacterials (antibiotics)
    • Difurazone (also known as Nitrovin) — an antibacterial growth promoter used in the animal feeds
    • Furazolidone
    • Nifurfoline
    • Nifuroxazide
    • Nifurquinazol
    • Nifurtoinol
    • Nifurzide
    • Nitrofural (also known as nitrofurazone)
    • Nitrofurantoin — a drug used to treat urinary tract infections[3]
    • Ranbezolid — technically an oxazolidinone antibiotic bearing a nitrofuran group
  • Antimicrobials
    • Furaltadone — an antiprotozoal
    • Furazidine — an antibacterial and antiprotozoal
    • Furylfuramide — a formerly used food preservative
    • Nifuratel — an antiprotozoal and antifungal
    • Nifurtimox — an antiprotozoal
  • FANFT, a potent nitrofuran derivative tumor initiator. It causes bladder tumors in all animals studied and is mutagenic to many bacteria.

References

1. ^{{cite journal|title=Residue Depletion of Nitrofuran Drugs and Their Tissue-Bound Metabolites in Channel Catfish (Ictalurus punctatus) after Oral Dosing|journal=Journal of Agricultural and Food Chemistry|volume=56|issue=17|pages=8030–8034|doi=10.1021/jf801398p|pmid=18698789|year=2008|last1=Chu|first1=Pak-Sin|last2=Lopez|first2=Mayda I|last3=Abraham|first3=Ann|last4=El Said|first4=Kathleen R|last5=Plakas|first5=Steven M}}
2. ^{{cite journal|title=Nitrofuran antibiotics: a review on the application, prohibition and residual analysis|journal=Veterinární Medicína|volume=53|pages=469–500|doi=10.17221/1979-VETMED|year=2008|last1=Vass|first1=M|last2=Hruska|first2=K|last3=Franek|first3=M}}
3. ^{{cite journal|title=Nitrofurantoin revisited: a systematic review and meta-analysis of controlled trials|journal=Journal of Antimicrobial Chemotherapy|volume=70|issue=9|pages=2456–2464|doi=10.1093/jac/dkv147|pmid=26066581|year=2015|last1=Huttner|first1=Angela|last2=Verhaegh|first2=Els M|last3=Harbarth|first3=Stephan|last4=Muller|first4=Anouk E|last5=Theuretzbacher|first5=Ursula|last6=Mouton|first6=Johan W}}

External links

  • {{MeshName|Nitrofurans}}
{{Nucleic acid inhibitors}}{{Antiprotozoal agent}}

1 : Nitrofurans
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