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词条 NKG2
释义

  1. See also

  2. References

  3. External links

{{infobox protein
|Name=killer cell lectin-like receptor subfamily C, member 1
|caption=
|image=
|width=
|HGNCid=6374
|Symbol=KLRC1
|AltSymbols=NKG2, NKG2-A, NKG2-B, CD159a
|EntrezGene=3821
|OMIM=161555
|RefSeq=NM_007328
|UniProt=P26715
|PDB=
|ECnumber=
|Chromosome=12
|Arm=p
|Band=13
|LocusSupplementaryData=
}}

NKG2 also known as CD159 (Cluster of Differentiation 159) is a receptor for natural killer cells. There are 7 NKG2 types: A, B, C, D, E, F and H. NKG2D is an activating receptor on the NK cell surface. NKG2A dimerizes with CD94 to make an inhibitory receptor (CD94/NKG2).

IPH2201 is a monoclonal antibody targeted at NKG2A.[1]

See also

  • Cluster of differentiation
  • CD94/NKG2

References

1. ^AstraZeneca Inks $1.8B in Immuno-Oncology Deals as Q1 Profit Dips

External links

  • {{MeshName|NKG2+protein}}
{{Clusters of differentiation}}{{immunology-stub}}

1 : Clusters of differentiation

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