| 词条 | Nodular fasciitis |
| 释义 |
| name = Nodular fasciitis | synonyms = | image = Nodular_fasciitis_-_high_mag.jpg | caption = Micrograph of nodular fasciitis showing the haphazard arrangement of cells (tissue culture-like pattern). H&E stain. | pronounce = | field = | symptoms = | complications = | onset = | duration = | types = | causes = | risks = | diagnosis = | differential = | prevention = | treatment = | medication = | prognosis = | frequency = | deaths = }}Nodular fasciitis, also known as nodular pseudosarcomatous fasciitis,[1] pseudosarcomatous fasciitis,[1] and subcutaneous pseudosarcomatous fibromatosis,[1]{{rp|992}} is a benign[2] soft tissue lesion most commonly found in the superficial fascia. The lesion commonly occurs in the first three decades of life. Upper extremities and trunk are the most common affected anatomical areas. Previous history of trauma may be present. Clinically and histologically, nodular fasciitis may be mistaken for a sarcoma.[3] Cause and clinical courseUntil recently, nodular fasciitis have been considered a reactive process of uncertain cause.[4] However, recent findings indicate that nodular fasciitis is a self-limited clonal neoplastic process (see below). Clinically, nodular fasciitis presents as a subcutaneous "growth" over a period of 3–6 weeks that eventually regresses. The lesion usually reaches a size of 2–3 cm. Larger lesions are unusual. Local recurrence has been described after simple surgical excision but it is rare. Histology
TreatmentSurgical excision is usually curative. Intralesional application of steroids has been used to induce regression. Because recurrence is rare, even when there is incomplete excision, in case of recurrence initial diagnosis of nodular fasciitis should be revisited.[5] See also
References1. ^{{cite book | last1 = Rapini | first1 = Ronald P | last2 = Bolognia | first2 = Jean L | last3 = Jorizzo | first3 = Joseph L | name-list-format = vanc |title=Dermatology: 2-Volume Set |publisher=Mosby |location=St. Louis |year=2007 |pages= |isbn=1-4160-2999-0 }} 2. ^{{cite journal | vauthors = Sailon AM, Cappuccino G, Hameed M, Fleegler EJ | title = Nodular fasciitis of the hand over the metacarpophalangeal joint: a case report | journal = Eplasty | volume = 8 | issue = | pages = e38 | date = July 2008 | pmid = 18725954 | pmc = 2491338 | doi = }} 3. ^1 2 {{cite book | editor-first1 = Irwin M | editor-last1 = Freedberg | editor-first2 = Arthur Z. | editor-last2 = Eisen | editor-first3 = Klauss | editor-last3 = Wolff | editor-first4 = K. Frank | editor-last4 = Austen | editor-first5 = Lowell A | editor-last5 = Goldsmith | editor-first6 = Stephen I. | editor-last6 = Katz | name-list-format = vanc | location = New York | year = 2003 | publisher = McGraw-Hill| volume = 1-2 | pages = 3328 pages| isbn = 978-0-07-138076-8 | title = Fitzpatrick's Dermatology in General Medicine }} 4. ^{{cite journal | vauthors = Oliveira AM, Chou MM | title = USP6-induced neoplasms: the biologic spectrum of aneurysmal bone cyst and nodular fasciitis | journal = Human Pathology | volume = 45 | issue = 1 | pages = 1–11 | date = January 2014 | pmid = 23769422 | doi = 10.1016/j.humpath.2013.03.005 }} 5. ^{{cite book | title = Bone and soft tissue pathology | date = 2012 | publisher = Elsevier/Saunders | vauthors = Horvai TE, Link TM | isbn = 978-1-4377-2520-9 | edition = 1st | location = Philadelphia, Pa. }} External links{{Medical resources| DiseasesDB = | ICD10 = {{ICD10|M|72|4|m|70}} | ICD9 = {{ICD9|728.79}} | ICDO = | OMIM = | MedlinePlus = | eMedicineSubj = | eMedicineTopic = | MeshID = }}{{Soft tissue disorders}}{{Soft tissue tumors and sarcomas}} 3 : Dermal and subcutaneous growths|Disorders of fascia|Soft tissue disorders |
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