| 词条 | Norfenefrine |
| 释义 |
| Verifiedfields = changed | verifiedrevid = 462263073 | IUPAC_name = 3-(2-amino-1-hydroxyethyl)phenol | image = Norfenefrine.png | image2 = (R)-Norfenefrine molecule ball.png | alt2 = Ball-and-stick model of (R)-Norfenefrine | tradename = | Drugs.com = {{drugs.com|international|norfenefrine}} | pregnancy_category = | legal_status = Rx-only | routes_of_administration = | bioavailability = | protein_bound = | metabolism = | elimination_half-life = | excretion = | CAS_number_Ref = {{cascite|changed|??}} | CAS_number = 536-21-0 | CAS_supplemental = 15308-34-6 (hydrochloride) | ATC_prefix = C01 | ATC_suffix = CA05 | PubChem = 4538 | ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} | ChemSpiderID = 4379 | UNII_Ref = {{fdacite|correct|FDA}} | UNII = D2P3M6SRN5 | KEGG_Ref = {{keggcite|correct|kegg}} | KEGG = D08286 | ChEMBL_Ref = {{ebicite|correct|EBI}} | ChEMBL = 358040 | C = 8 | H = 11 | N = 1 | O = 2 | molecular_weight = 153.178 g/mol | smiles = OC(c1cc(O)ccc1)CN | synonyms = Norfenephrine Norphenephrine Norphenylephrine meta-Norsynephrine meta-Octopamine 3-Octopamine | StdInChI_Ref = {{stdinchicite|correct|chemspider}} | StdInChI = 1S/C8H11NO2/c9-5-8(11)6-2-1-3-7(10)4-6/h1-4,8,10-11H,5,9H2 | StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} | StdInChIKey = LRCXRAABFLIVAI-UHFFFAOYSA-N }}Norfenefrine (INN) or meta-octopamine (3-octopamine), also known as 3,β-dihydroxyphenethylamine, is an adrenergic agent used as a sympathomimetic drug which is marketed in Europe, Japan, and Mexico.[1][2] Along with its structural isomer p-octopamine and the tyramines, norfenefrine is a naturally occurring, endogenous trace amine and plays a role as a minor neurotransmitter in the brain.[3] Some brand names for it include Coritat, Energona, Hypolind, and Novadral. See also
References1. ^{{cite book | author = Macdonald F | title = Dictionary of Pharmacological Agents | url = https://books.google.com/books?id=DeX7jgInYFMC&pg=PA104 | accessdate = 24 April 2012 | year = 1997 | publisher = CRC Press | isbn = 978-0-412-46630-4 | page = 104 }} {{Cardiac stimulants excluding cardiac glycosides}}{{Neurotransmitters}}{{TAAR ligands}}{{Phenethylamines}}{{nervous-system-drug-stub}}2. ^{{cite book | title = Index Nominum 2000: International Drug Directory | url = https://books.google.com/books?id=5GpcTQD_L2oC&pg=PA750 | accessdate = 24 April 2012 | year = 2000 | publisher = Taylor & Francis | isbn = 978-3-88763-075-1 | page = 750 }} 3. ^{{cite journal |vauthors=Danielson TJ, Boulton AA, Robertson HA | title = m-Octopamine, p-octopamine and phenylethanolamine in rat brain: a sensitive, specific assay and the effects of some drugs | journal = Journal of Neurochemistry | volume = 29 | issue = 6 | pages = 1131–5 |date=December 1977 | pmid = 340613 | doi = 10.1111/j.1471-4159.1977.tb06519.x| url = }} 8 : Alpha-adrenergic agonists|Cardiac stimulants|Norepinephrine-dopamine releasing agents|Neurotransmitters|Phenethylamines|Phenols|TAAR1 agonists|Trace amines |
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