| 词条 | Oxetacaine |
| 释义 |
| Verifiedfields = changed | verifiedrevid = 462267014 | IUPAC_name = 2,2'-(2-hydroxyethylimino)bis [N-(1,1-dimethyl-2- phenylethyl)-N-methylacetamide] | image = Oxetacaine.svg | width = 280 | tradename = | Drugs.com = {{drugs.com|international|oxetacaine}} | pregnancy_AU = | pregnancy_US = | pregnancy_category = | legal_AU = | legal_CA = | legal_UK = | legal_US = | legal_status = | routes_of_administration = Oral, topical | bioavailability = | protein_bound = | metabolism = | elimination_half-life = 1 hour | excretion = | CAS_number_Ref = {{cascite|changed|??}} | CAS_number = 126-27-2 | ATC_prefix = C05 | ATC_suffix = AD06 | PubChem = 4621 | DrugBank_Ref = {{drugbankcite|correct|drugbank}} | DrugBank = | ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} | ChemSpiderID = 4460 | UNII_Ref = {{fdacite|correct|FDA}} | UNII = IP8QT76V17 | KEGG_Ref = {{keggcite|correct|kegg}} | KEGG = D01152 | ChEMBL_Ref = {{ebicite|correct|EBI}} | ChEMBL = 127592 | C=28 | H=41 | N=3 | O=3 | molecular_weight = 467.643 g/mol | smiles = O=C(N(C(C)(C)Cc1ccccc1)C)CN(CCO)CC(=O)N(C(Cc2ccccc2)(C)C)C | StdInChI_Ref = {{stdinchicite|correct|chemspider}} | StdInChI = 1S/C28H41N3O3/c1-27(2,19-23-13-9-7-10-14-23)29(5)25(33)21-31(17-18-32)22-26(34)30(6)28(3,4)20-24-15-11-8-12-16-24/h7-16,32H,17-22H2,1-6H3 | StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} | StdInChIKey = FTLDJPRFCGDUFH-UHFFFAOYSA-N }} Oxetacaine (INN, also known as oxethazaine) is a potent local anesthetic. It is administered orally (usually in combination with an antacid) for the relief of pain associated with peptic ulcer disease or esophagitis. It is also used topically in the management of hemorrhoid pain. Oral oxetacaine preparations are available in several countries, including India, South Africa, Japan and Brazil, but not the United States. Unlike most local anesthetics, oxetacaine does not break down under strongly acidic conditions.[1] References1. ^{{cite journal |vauthors=Seifter J, Glassman JM, Hudyma GM |title=Oxethazaine and related congeners: a series of highly potent local anesthetics |journal=Proc Soc Exp Biol Med |volume=109 |issue= |pages=664–8 |year=1962 |pmid=13910333 |doi=10.3181/00379727-109-27300}} External links
3 : Local anesthetics|Acetamides|Alcohols |
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