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词条 Oxidative decarboxylation
释义

  1. Citric acid cycle

  2. Other occurrences

  3. References

Oxidative decarboxylation reactions are oxidation reactions in which a carboxylate group is removed, forming carbon dioxide. They often occur in biological systems: there are many examples in the citric acid cycle.

Citric acid cycle

In the citric acid cycle pyruvate dehydrogenase, isocitrate dehydrogenase, and α-ketoglutarate dehydrogenase catalyze oxidative decarboxylation reactions. Each reaction reduces NAD+ to NADH and generates CO2.[1]

Other occurrences

The transformation of glyoxylate to formic acid is also an oxidative decarboxylation.{{Citation needed|reason=nothing found on google about this reaction|date=January 2012}}

References

1. ^{{cite book|last1=Voet|first1=Donald|last2=Voet|first2=Judith|last3=Pratt|first3=Charlotte|title=Fundamentals of Biochemistry|edition=4|year=2013|publisher=John Wiley and Sons|isbn=9780470547847|pages=555–565}}

1 : Substitution reactions

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