词条 | Oxomemazine |
释义 |
| Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 447980724 | IUPAC_name = 3-(5,5-Dioxido-10H-phenothiazin-10-yl)-N,N,2-trimethylpropan-1-amine | image = oxomemazine.png | width = 150 | tradename = | Drugs.com = {{drugs.com|international|oxomemazine}} | pregnancy_category = | legal_US = Not approved | legal_status = Rx-only | routes_of_administration = | bioavailability = | protein_bound = | metabolism = | elimination_half-life = | excretion = | CAS_number_Ref = {{cascite|correct|??}} | CAS_number = 3689-50-7 | ATC_prefix = R06 | ATC_suffix = AD08 | PubChem = 19396 | ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} | ChemSpiderID = 18281 | ChEMBL_Ref = {{ebicite|changed|EBI}} | ChEMBL = 2104734 | UNII_Ref = {{fdacite|correct|FDA}} | UNII = 305MB38V1C | KEGG_Ref = {{keggcite|correct|kegg}} | KEGG = D07401 | C=18 | H=22 | N=2 | O=2 | S=1 | molecular_weight = 330.444 g/mol | smiles = O=S3(=O)c1ccccc1N(c2c3cccc2)CC(C)CN(C)C | StdInChI_Ref = {{stdinchicite|correct|chemspider}} | StdInChI = 1S/C18H22N2O2S/c1-14(12-19(2)3)13-20-15-8-4-6-10-17(15)23(21,22)18-11-7-5-9-16(18)20/h4-11,14H,12-13H2,1-3H3 | StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} | StdInChIKey = QTQPVLDZQVPLGV-UHFFFAOYSA-N }}Oxomemazine is an antihistamine and anticholinergic of the phenothiazine chemical class for the treatment of cough.[1][2] See also
References1. ^{{Cite journal | last1 = Pujet | first1 = J. C. | last2 = Keddad | first2 = K. | last3 = Sévenier | first3 = F. | last4 = Jolivet-Landreau | first4 = I. | title = Comparative study of two antitussive drugs in the treatment of acute dry cough of infectious origin (prospective, randomized, single blind study) | journal = Thérapie | volume = 57 | issue = 5 | pages = 457–463 | year = 2002 | pmid = 12611200}} {{Antihistamines}}{{Cholinergics}}{{Histaminergics}}{{Tricyclics}}{{respiratory-system-drug-stub}}2. ^{{Cite journal | doi = 10.1007/BF02979123 | last1 = Lee | first1 = S. W. | last2 = Woo | first2 = C. W. | last3 = Kim | first3 = J. G. | title = Selectivity of oxomemazine for the M1 muscarinic receptors | journal = Archives of Pharmacal Research | volume = 17 | issue = 6 | pages = 443–451 | year = 1994 | pmid = 10319156}} 5 : Phenothiazines|Sulfones|Amines|Antihistamines|Sedatives |
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