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词条 Oxomemazine
释义

  1. See also

  2. References

{{Drugbox
| Verifiedfields = changed
| Watchedfields = changed
| verifiedrevid = 447980724
| IUPAC_name = 3-(5,5-Dioxido-10H-phenothiazin-10-yl)-N,N,2-trimethylpropan-1-amine
| image = oxomemazine.png
| width = 150
| tradename =
| Drugs.com = {{drugs.com|international|oxomemazine}}
| pregnancy_category =
| legal_US = Not approved
| legal_status = Rx-only
| routes_of_administration =
| bioavailability =
| protein_bound =
| metabolism =
| elimination_half-life =
| excretion =
| CAS_number_Ref = {{cascite|correct|??}}
| CAS_number = 3689-50-7
| ATC_prefix = R06
| ATC_suffix = AD08
| PubChem = 19396
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
| ChemSpiderID = 18281
| ChEMBL_Ref = {{ebicite|changed|EBI}}
| ChEMBL = 2104734
| UNII_Ref = {{fdacite|correct|FDA}}
| UNII = 305MB38V1C
| KEGG_Ref = {{keggcite|correct|kegg}}
| KEGG = D07401
| C=18 | H=22 | N=2 | O=2 | S=1
| molecular_weight = 330.444 g/mol
| smiles = O=S3(=O)c1ccccc1N(c2c3cccc2)CC(C)CN(C)C
| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
| StdInChI = 1S/C18H22N2O2S/c1-14(12-19(2)3)13-20-15-8-4-6-10-17(15)23(21,22)18-11-7-5-9-16(18)20/h4-11,14H,12-13H2,1-3H3
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
| StdInChIKey = QTQPVLDZQVPLGV-UHFFFAOYSA-N
}}Oxomemazine is an antihistamine and anticholinergic of the phenothiazine chemical class for the treatment of cough.[1][2]

See also

  • Oxomemazine/guaifenesin

References

1. ^{{Cite journal | last1 = Pujet | first1 = J. C. | last2 = Keddad | first2 = K. | last3 = Sévenier | first3 = F. | last4 = Jolivet-Landreau | first4 = I. | title = Comparative study of two antitussive drugs in the treatment of acute dry cough of infectious origin (prospective, randomized, single blind study) | journal = Thérapie | volume = 57 | issue = 5 | pages = 457–463 | year = 2002 | pmid = 12611200}}
2. ^{{Cite journal | doi = 10.1007/BF02979123 | last1 = Lee | first1 = S. W. | last2 = Woo | first2 = C. W. | last3 = Kim | first3 = J. G. | title = Selectivity of oxomemazine for the M1 muscarinic receptors | journal = Archives of Pharmacal Research | volume = 17 | issue = 6 | pages = 443–451 | year = 1994 | pmid = 10319156}}
{{Antihistamines}}{{Cholinergics}}{{Histaminergics}}{{Tricyclics}}{{respiratory-system-drug-stub}}

5 : Phenothiazines|Sulfones|Amines|Antihistamines|Sedatives

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