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词条 Phosphodiesterase I
释义

  1. See also

  2. References

  3. External links

{{Infobox enzyme
| Name = Phosphodiesterase I
| EC_number = 3.1.4.1
| CAS_number = 9025-82-5
| IUBMB_EC_number = 3/1/4/1
| GO_code =
| image =
| width =
| caption =
}}Phosphodiesterase I ({{EC number|3.1.4.1}}, 5'-exonuclease, 5'-phosphodiesterase, 5'-nucleotide phosphodiesterase, oligonucleate 5'-nucleotidohydrolase, 5' nucleotide phosphodiesterase/alkaline phosphodiesterase I, 5'-NPDase, 5'-PDase, 5'-PDE, 5'NPDE, alkaline phosphodiesterase, nucleotide pyrophosphatase/phosphodiesterase I, orthophosphoric diester phosphohydrolase, PDE I, phosphodiesterase, exonuclease I) is an enzyme with systematic name oligonucleotide 5'-nucleotidohydrolase.[1] This enzyme catalyses the following chemical reaction

Hydrolytically removes 5'-nucleotides successively from the 3'-hydroxy termini of 3'-hydroxy-terminated oligonucleotides

Hydrolyses both ribonucleotides and deoxyribonucleotides. Has low activity towards polynucleotides.

See also

  • Phosphodiesterase

References

1. ^{{cite book | chapter = Phosphodiesterases | title = The Enzymes |author = Khorana, G.H. |year = 1961 |volume = 5 |pages = 79–94 |veditors = Boyer PD, Lardy H, Myrbäck K |edition = 2nd |publisher = Academic Press |location = New York }}

External links

  • {{MeshName|Phosphodiesterase+I}}
{{Esterases}}{{Enzymes}}{{Portal bar|Molecular and Cellular Biology|border=no}}

1 : EC 3.1.4

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