词条 | Prenoxdiazine |
释义 |
| verifiedrevid = 464214020 | IUPAC_name = 1-[2-[3-(2,2-diphenylethyl)-1,2,4-oxadiazol-5-yl]ethyl]piperidine | image = Prenoxdiazine.png | tradename = Libexin | Drugs.com = {{drugs.com|international|prenoxdiazine}} | pregnancy_AU = | pregnancy_US = | pregnancy_category = | legal_AU = | legal_CA = | legal_UK = | legal_US = | legal_status = | routes_of_administration = | bioavailability = | protein_bound = | metabolism = | elimination_half-life = | excretion = | CAS_number_Ref = {{cascite|correct|??}} | CAS_number = 982-43-4 | ATC_prefix = R05 | ATC_suffix = DB18 | PubChem = 120508 | DrugBank_Ref = {{drugbankcite|correct|drugbank}} | DrugBank = | ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} | ChemSpiderID = 107586 | UNII_Ref = {{fdacite|correct|FDA}} | UNII = S491HH391H | C=23 | H=27 | N=3 | O=1 | molecular_weight = 361.48 g/mol | smiles = n1c(onc1CC(c2ccccc2)c3ccccc3)CCN4CCCCC4 | StdInChI_Ref = {{stdinchicite|correct|chemspider}} | StdInChI = 1S/C23H27N3O/c1-4-10-19(11-5-1)21(20-12-6-2-7-13-20)18-22-24-23(27-25-22)14-17-26-15-8-3-9-16-26/h1-2,4-7,10-13,21H,3,8-9,14-18H2 | StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} | StdInChIKey = PXZDWASDNFWKSD-UHFFFAOYSA-N }} Prenoxdiazine (marketed as Libexin) is a cough suppressant.[1] It acts peripherally by desensitizing the pulmonary stretch receptors. Therefore there's a reduction of cough impulses originating in the lungs. Prenoxdiazine is indicated in cough of bronchial origin. References1. ^{{Cite journal | last1 = Csürös | first1 = L. | title = Fifteen years of experience on the use of Libexin tablets | journal = Therapia Hungarica (English edition) | volume = 37 | issue = 1 | pages = 50–54 | year = 1989 | pmid = 2667194}} {{Cough and cold preparations}}{{respiratory-system-drug-stub}} 3 : Antitussives|Piperidines|Oxadiazoles |
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