“Preprotachykinin”的意思、由来-开放百科全书

词条

Preprotachykinin

释义

References

Preprotachykinins are precursor proteins that are modified into tachykinin peptides. Via alternative splicing and post-translational modifications, preprotachykinins produce multiple peptide neurotransmitters.

There are two human preprotachykinins:^[1]

preprotachykinin-1 (also PPT-1, PPT-I, or PPT-A), which produces substance P and neurokinin A (also called "substance K"), and the derived neuropeptide K and neurokinin gamma.
preprotachykinin-2 (also PPT-2, PPT-II, or PPT-B), which produces neurokinin B.

References

1. ^{{Cite journal|vauthors=Helke CJ, Krause JE, Mantyh PW, Couture R, Bannon MJ |date=1 April 1990|title=Diversity in mammalian tachykinin peptidergic neurons: multiple peptides, receptors, and regulatory mechanisms|journal=FASEB Journal|doi=|pmid=1969374|volume=4|pages=1606–15}}

2 : Neuropeptides|Precursor proteins

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