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词条 Protease-sparing regimen
释义

  1. See also

  2. References

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}}Protease-sparing regimen, often abbreviated as PSR, is a method or therapy for treating people infected with HIV that involves a three-drug combination that reduces viral load below the limit of detection while saving protease inhibitors for later use. It is considered a weaker (in terms of quantity and concentration) form of HIV treatment. It has been argued that such a regimen is not as potent as giving HIV patients with the strongest drugs as soon as it is detected. Others believe that this might be considered a long-term strategy in order to reduce the amount of HIV,[1] and in some instances have proven to be successful.[2]

See also

  • Protease
  • Women's Interagency HIV Study

References

1. ^{{cite journal |vauthors=Corales RB, Shrestha NK, Taege AJ, etal |title=Protease-sparing regimen in a real-life practice with naïve patients: an equal opportunity approach? |journal=HIV Clin Trials |volume=2 |issue=1 |pages=17–21 |year=2001 |pmid=11590510 |url=http://thomasland.metapress.com/openurl.asp?genre=article&issn=1528-4336&volume=2&issue=1&spage=17|doi=10.1310/2V0B-HDWC-AGWR-H56M }}
2. ^{{cite journal |vauthors=Van der Linden D, Hainaut M, Goetghebuer T, etal |title=Effectiveness of early initiation of protease inhibitor-sparing antiretroviral regimen in human immunodeficiency virus-1 vertically infected infants |journal=Pediatr. Infect. Dis. J. |volume=26 |issue=4 |pages=359–61 |date=April 2007 |pmid=17414406 |doi=10.1097/01.inf.0000258626.34984.eb |url=http://meta.wkhealth.com/pt/pt-core/template-journal/lwwgateway/media/landingpage.htm?issn=0891-3668&volume=26&issue=4&spage=359|hdl=2078/119175 }}
  • https://web.archive.org/web/20070927190712/http://www.projinf.org/pip/26/pip26i.html
  • https://web.archive.org/web/20070927190717/http://www.projinf.org/pip/25/pip25a.html
  • {{cite conference |title=Protease Sparing Regimen in a Real Life Practice with Naive Patients: An Equal Opportunity Approach? |booktitle=13th International AIDS Conference |date=July 9–14, 2000 |location=Durban, South Africa |url=http://www.aegis.com/conferences/iac/2000/WePeB4134.html |id=WePeB4134 }}
  • http://www.aids-ed.org/aidsetc?page=et-14-00-02
  • http://www.medscape.com/viewarticle/418668
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1 : HIV/AIDS

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