| 词条 | Quinuclidine |
| 释义 |
| Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 464379026 | Reference =[1] | ImageFileL1_Ref = {{chemboximage|correct|??}} | ImageFileL1 = Quinuclidine.svg | ImageSizeL1 = 200px | ImageNameL1 = Skeletal formula of quinuclidine | ImageFileR1 = Quinuclidine 3D.png | ImageSizeR1 = 200px | ImageNameR1 = Ball-and-stick model of quinuclidine | PIN = 1-Azabicyclo[2.2.2]octane[2] | OtherNames = Quinuclidine[2] |Section1={{Chembox Identifiers | ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} | ChemSpiderID = 7246 | InChI = 1/C7H13N/c1-4-8-5-2-7(1)3-6-8/h7H,1-6H2 | InChIKey = SBYHFKPVCBCYGV-UHFFFAOYAA | ChEMBL_Ref = {{ebicite|correct|EBI}} | ChEMBL = 1209648 | StdInChI_Ref = {{stdinchicite|correct|chemspider}} | StdInChI = 1S/C7H13N/c1-4-8-5-2-7(1)3-6-8/h7H,1-6H2 | StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} | StdInChIKey = SBYHFKPVCBCYGV-UHFFFAOYSA-N | CASNo_Ref = {{cascite|correct|CAS}} | CASNo = 100-76-5 | UNII_Ref = {{fdacite|changed|FDA}} | UNII = XFX99FC5VI | PubChem = 7527 | ChEBI_Ref = {{ebicite|correct|EBI}} | ChEBI = 38420 | SMILES = N12CCC(CC1)CC2 }} |Section2={{Chembox Properties | C=7 | H=13 | N=1 | Appearance = | Density = 0.97 g/cm3 | MeltingPtC = 157 to 160 | MeltingPt_notes = | BoilingPtC = 149.5 | BoilingPt_notes = at 760 mmHg | Solubility = | pKa = 11.0 (conjugate acid) |Section3={{Chembox Hazards | MainHazards = | FlashPtC = 36.5 | AutoignitionPtC = }} Quinuclidine is an organic compound and a bicyclic amine and used as a catalyst and a chemical building block. It is a strong base with pKa of the conjugate acid of 11.0.[3] This is due to greater availability of the nitrogen lone pair.{{Citation needed|date=February 2007}} It can be prepared by reduction of quinuclidone. The compound is structurally related to DABCO, in which the other bridgehead is also nitrogen, and to tropane, which has a slightly different carbon frame. Quinuclidine is found as a structural component of some biomolecules including quinine. References1. ^Quinuclidine {{webarchive |url=https://web.archive.org/web/20071015200029/http://www.sigmaaldrich.com/catalog/search/ProductDetail?ProdNo=22709&Brand=FLUKA |date=October 15, 2007 }} at Sigma-Aldrich 2. ^1 {{cite book | title = Nomenclature of Organic Chemistry : IUPAC Recommendations and Preferred Names 2013 (Blue Book) | publisher = The Royal Society of Chemistry | date = 2014 | location = Cambridge | page = 169 | doi = 10.1039/9781849733069-FP001 | isbn = 978-0-85404-182-4 | quote = The name quinuclidine is retained for general nomenclature only (see Table 2.6).}} 3. ^{{cite journal |title=Azatriquinanes: Synthesis, Structure, and Reactivity |author1=Hext, N. M. |author2=Hansen, J. |author3=Blake, A. J. |author4=Hibbs, D. E. |author5=Hursthouse, M. B. |author6=Shishkin, O. V. |author7=Mascal, M. |journal=J. Org. Chem. |year=1998 |volume=63 |issue=17 |pages=6016–6020 |doi=10.1021/jo980788s |pmid=11672206}} 1 : Quinuclidines |
| 随便看 |
|
开放百科全书收录14589846条英语、德语、日语等多语种百科知识，基本涵盖了大多数领域的百科知识，是一部内容自由、开放的电子版国际百科全书。