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词条 RELB
释义

  1. Interactions

  2. See also

  3. References

  4. Further reading

{{Infobox_gene}}Transcription factor RelB is a protein that in humans is encoded by the RELB gene.[1]

Interactions

RELB has been shown to interact with NFKB2,[2][3] NFKB1,[2] and C22orf25.[4]

See also

  • NF-κB

References

1. ^{{cite journal | vauthors = Bours V, Burd PR, Brown K, Villalobos J, Park S, Ryseck RP, Bravo R, Kelly K, Siebenlist U | title = A novel mitogen-inducible gene product related to p50/p105-NF-kappa B participates in transactivation through a kappa B site | journal = Molecular and Cellular Biology | volume = 12 | issue = 2 | pages = 685–95 | date = Feb 1992 | pmid = 1531086 | pmc = 364259 | doi = }}
2. ^1 {{cite journal | vauthors = Bouwmeester T, Bauch A, Ruffner H, Angrand PO, Bergamini G, Croughton K, Cruciat C, Eberhard D, Gagneur J, Ghidelli S, Hopf C, Huhse B, Mangano R, Michon AM, Schirle M, Schlegl J, Schwab M, Stein MA, Bauer A, Casari G, Drewes G, Gavin AC, Jackson DB, Joberty G, Neubauer G, Rick J, Kuster B, Superti-Furga G | title = A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway | journal = Nature Cell Biology | volume = 6 | issue = 2 | pages = 97–105 | date = Feb 2004 | pmid = 14743216 | doi = 10.1038/ncb1086 }}
3. ^{{cite journal | vauthors = Thornburg NJ, Pathmanathan R, Raab-Traub N | title = Activation of nuclear factor-kappaB p50 homodimer/Bcl-3 complexes in nasopharyngeal carcinoma | journal = Cancer Research | volume = 63 | issue = 23 | pages = 8293–301 | date = Dec 2003 | pmid = 14678988 }}
4. ^{{cite web|title=Molecular Interaction Database|url=http://mint.bio.uniroma2.it/mint/Welcome.do|archive-url=https://web.archive.org/web/20060506110418/http://mint.bio.uniroma2.it/mint/Welcome.do|dead-url=yes|archive-date=2006-05-06}}

Further reading

{{refbegin | 2}}
  • {{cite journal | vauthors = Taylor JP, Pomerantz R, Bagasra O, Chowdhury M, Rappaport J, Khalili K, Amini S | title = TAR-independent transactivation by Tat in cells derived from the CNS: a novel mechanism of HIV-1 gene regulation | journal = The EMBO Journal | volume = 11 | issue = 9 | pages = 3395–403 | date = Sep 1992 | pmid = 1505523 | pmc = 556874 | doi = }}
  • {{cite journal | vauthors = Ruben SM, Klement JF, Coleman TA, Maher M, Chen CH, Rosen CA | title = I-Rel: a novel rel-related protein that inhibits NF-kappa B transcriptional activity | journal = Genes & Development | volume = 6 | issue = 5 | pages = 745–60 | date = May 1992 | pmid = 1577270 | doi = 10.1101/gad.6.5.745 }}
  • {{cite journal | vauthors = Liu J, Perkins ND, Schmid RM, Nabel GJ | title = Specific NF-kappa B subunits act in concert with Tat to stimulate human immunodeficiency virus type 1 transcription | journal = Journal of Virology | volume = 66 | issue = 6 | pages = 3883–7 | date = Jun 1992 | pmid = 1583734 | pmc = 241175 | doi = }}
  • {{cite journal | vauthors = Biswas DK, Salas TR, Wang F, Ahlers CM, Dezube BJ, Pardee AB | title = A Tat-induced auto-up-regulatory loop for superactivation of the human immunodeficiency virus type 1 promoter | journal = Journal of Virology | volume = 69 | issue = 12 | pages = 7437–44 | date = Dec 1995 | pmid = 7494249 | pmc = 189681 | doi = }}
  • {{cite journal | vauthors = Jeang KT, Chun R, Lin NH, Gatignol A, Glabe CG, Fan H | title = In vitro and in vivo binding of human immunodeficiency virus type 1 Tat protein and Sp1 transcription factor | journal = Journal of Virology | volume = 67 | issue = 10 | pages = 6224–33 | date = Oct 1993 | pmid = 7690421 | pmc = 238044 | doi = }}
  • {{cite journal | vauthors = Alcamí J, Laín de Lera T, Folgueira L, Pedraza MA, Jacqué JM, Bachelerie F, Noriega AR, Hay RT, Harrich D, Gaynor RB | title = Absolute dependence on kappa B responsive elements for initiation and Tat-mediated amplification of HIV transcription in blood CD4 T lymphocytes | journal = The EMBO Journal | volume = 14 | issue = 7 | pages = 1552–60 | date = Apr 1995 | pmid = 7729429 | pmc = 398242 | doi = }}
  • {{cite journal | vauthors = Majello B, De Luca P, Hagen G, Suske G, Lania L | title = Different members of the Sp1 multigene family exert opposite transcriptional regulation of the long terminal repeat of HIV-1 | journal = Nucleic Acids Research | volume = 22 | issue = 23 | pages = 4914–21 | date = Nov 1994 | pmid = 7800480 | pmc = 523756 | doi = 10.1093/nar/22.23.4914 }}
  • {{cite journal | vauthors = Taylor JP, Pomerantz RJ, Oakes JW, Khalili K, Amini S | title = A CNS-enriched factor that binds to NF-kappa B and is required for interaction with HIV-1 tat | journal = Oncogene | volume = 10 | issue = 2 | pages = 395–400 | date = Jan 1995 | pmid = 7838536 | doi = }}
  • {{cite journal | vauthors = Westendorp MO, Shatrov VA, Schulze-Osthoff K, Frank R, Kraft M, Los M, Krammer PH, Dröge W, Lehmann V | title = HIV-1 Tat potentiates TNF-induced NF-kappa B activation and cytotoxicity by altering the cellular redox state | journal = The EMBO Journal | volume = 14 | issue = 3 | pages = 546–54 | date = Feb 1995 | pmid = 7859743 | pmc = 398112 | doi = }}
  • {{cite journal | vauthors = Scala G, Ruocco MR, Ambrosino C, Mallardo M, Giordano V, Baldassarre F, Dragonetti E, Quinto I, Venuta S | title = The expression of the interleukin 6 gene is induced by the human immunodeficiency virus 1 TAT protein | journal = The Journal of Experimental Medicine | volume = 179 | issue = 3 | pages = 961–71 | date = Mar 1994 | pmid = 8113688 | pmc = 2191426 | doi = 10.1084/jem.179.3.961 }}
  • {{cite journal | vauthors = Bours V, Azarenko V, Dejardin E, Siebenlist U | title = Human RelB (I-Rel) functions as a kappa B site-dependent transactivating member of the family of Rel-related proteins | journal = Oncogene | volume = 9 | issue = 6 | pages = 1699–702 | date = Jun 1994 | pmid = 8183565 | doi = }}
  • {{cite journal | vauthors = Deloukas P, Dauwerse JG, van Ommen GJ, van Loon AP | title = The human NFKB3 gene encoding the p65 subunit of transcription factor NF-kappa B is located on chromosome 11q12 | journal = Genomics | volume = 19 | issue = 3 | pages = 592–4 | date = Feb 1994 | pmid = 8188306 | doi = 10.1006/geno.1994.1115 }}
  • {{cite journal | vauthors = Westendorp MO, Li-Weber M, Frank RW, Krammer PH | title = Human immunodeficiency virus type 1 Tat upregulates interleukin-2 secretion in activated T cells | journal = Journal of Virology | volume = 68 | issue = 7 | pages = 4177–85 | date = Jul 1994 | pmid = 8207793 | pmc = 236340 | doi = }}
  • {{cite journal | vauthors = Dobrzanski P, Ryseck RP, Bravo R | title = Both N- and C-terminal domains of RelB are required for full transactivation: role of the N-terminal leucine zipper-like motif | journal = Molecular and Cellular Biology | volume = 13 | issue = 3 | pages = 1572–82 | date = Mar 1993 | pmid = 8441398 | pmc = 359469 | doi = }}
  • {{cite journal | vauthors = Harhaj E, Blaney J, Millhouse S, Sun SC | title = Differential effects of I kappa B molecules on Tat-mediated transactivation of HIV-1 LTR | journal = Virology | volume = 216 | issue = 1 | pages = 284–7 | date = Feb 1996 | pmid = 8615004 | doi = 10.1006/viro.1996.0062 }}
  • {{cite journal | vauthors = Conant K, Ma M, Nath A, Major EO | title = Extracellular human immunodeficiency virus type 1 Tat protein is associated with an increase in both NF-kappa B binding and protein kinase C activity in primary human astrocytes | journal = Journal of Virology | volume = 70 | issue = 3 | pages = 1384–9 | date = Mar 1996 | pmid = 8627654 | pmc = 189957 | doi = }}
  • {{cite journal | vauthors = Demarchi F, d'Adda di Fagagna F, Falaschi A, Giacca M | title = Activation of transcription factor NF-kappaB by the Tat protein of human immunodeficiency virus type 1 | journal = Journal of Virology | volume = 70 | issue = 7 | pages = 4427–37 | date = Jul 1996 | pmid = 8676466 | pmc = 190376 | doi = }}
  • {{cite journal | vauthors = Beauparlant P, Kwon H, Clarke M, Lin R, Sonenberg N, Wainberg M, Hiscott J | title = Transdominant mutants of I kappa B alpha block Tat-tumor necrosis factor synergistic activation of human immunodeficiency virus type 1 gene expression and virus multiplication | journal = Journal of Virology | volume = 70 | issue = 9 | pages = 5777–85 | date = Sep 1996 | pmid = 8709193 | pmc = 190591 | doi = }}
  • {{cite journal | vauthors = Ramazzotti E, Vignoli M, Re MC, Furlini G, La Placa M | title = Enhanced nuclear factor-kappa B activation induced by tumour necrosis factor-alpha in stably tat-transfected cells is associated with the presence of cell-surface-bound Tat protein | journal = AIDS | volume = 10 | issue = 5 | pages = 455–61 | date = May 1996 | pmid = 8724035 | doi = 10.1097/00002030-199605000-00002 }}
{{refend}}{{PDB Gallery|geneid=5971}}{{Transcription factors|g4}}{{DEFAULTSORT:Relb}}{{gene-19-stub}}

1 : Transcription factors
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