| 词条 | Rescinnamine |
| 释义 |
| verifiedrevid = 464380960 | IUPAC_name = methyl (3β,16β,17α,18β,20α)-11,17-dimethoxy-18- | image = Rescinnamine.svg | width = 300 | tradename = Moderil, Cinnasil, Anaprel | pregnancy_category = | legal_status = Rx-only | routes_of_administration = oral | bioavailability = | protein_bound = | metabolism = | elimination_half-life = | IUPHAR_ligand = 7098 | CAS_number_Ref = {{cascite|correct|??}} | CAS_number = 24815-24-5 | ATC_prefix = C02 | ATC_suffix = AA01 | ATC_supplemental = | PubChem = 5280954 | DrugBank_Ref = {{drugbankcite|correct|drugbank}} | DrugBank = DB01180 | ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} | ChemSpiderID = 4444446 | UNII_Ref = {{fdacite|correct|FDA}} | UNII = Q6W1F7DJ2D | KEGG_Ref = {{keggcite|correct|kegg}} | KEGG = D00198 | ChEBI_Ref = {{ebicite|correct|EBI}} | ChEBI = 28572 | ChEMBL_Ref = {{ebicite|correct|EBI}} | ChEMBL = 1668 | C=35 | H=42 | N=2 | O=9 | molecular_weight = 634.716 g/mol | smiles = [H][C@]26C[C@@H](OC(=O)/C=C/c1cc(OC)c(OC)c(OC)c1)[C@H](OC)[C@@H](C(=O)OC)[C@@]2([H])C[C@]5([H])c4[nH]c3cc(OC)ccc3c4CCN5C6 | StdInChI_Ref = {{stdinchicite|correct|chemspider}} | StdInChI = 1S/C35H42N2O9/c1-40-21-8-9-22-23-11-12-37-18-20-15-29(46-30(38)10-7-19-13-27(41-2)33(43-4)28(14-19)42-3)34(44-5)31(35(39)45-6)24(20)17-26(37)32(23)36-25(22)16-21/h7-10,13-14,16,20,24,26,29,31,34,36H,11-12,15,17-18H2,1-6H3/b10-7+/t20-,24+,26-,29-,31+,34+/m1/s1 | StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} | StdInChIKey = SZLZWPPUNLXJEA-QEGASFHISA-N | synonyms = methyl (1R,15S,17R,18R,19S,20S)-6,18-dimethoxy-17- }} Rescinnamine, known by the brand names moderil, cinnasil, and anaprel, is an angiotensin-converting enzyme inhibitor used as an antihypertensive drug. It is a vinca alkaloid obtained from Rauwolfia serpentina[1] and other species of Rauwolfia.[2] References1. ^{{cite journal |vauthors=FIFE R, MACLAURIN JC, WRIGHT JH |title=Rescinnamine in treatment of hypertension in hospital clinic and in general practice |journal=British Medical Journal |volume=2 |issue=5216 |pages=1848–50 |date=December 1960 |pmid=13699407 |pmc=2098607 |doi= 10.1136/bmj.2.5216.1848|url=}} {{Antihypertensives and diuretics}}{{Angiotensin receptor modulators}}{{Antihypertensive-stub}}2. ^{{cite journal |journal = Planta Med. |year = 1982 |volume = 44 |issue = 2 |pages = 91-3 |title = Alkaloids of Vinca major cv. Variegata. |vauthors = Balsevich J, Constabel F, Kurz WG |pmid = 17402086 |doi=10.1055/s-2007-971409}} 5 : ACE inhibitors|Antihypertensive agents|Alkaloids found in Rauvolfia|Phenol ethers|Cinnamates |
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