“Ribitol 2-dehydrogenase”的意思、由来-开放百科全书

词条

Ribitol 2-dehydrogenase

释义

Nomenclature
References

{{enzyme
| Name = ribitol 2-dehydrogenase
| EC_number = 1.1.1.56
| CAS_number = 9014-23-7
| IUBMB_EC_number = 1/1/1/56
| GO_code = 0050255
| image =
| width =
| caption =
}}

In enzymology, a ribitol 2-dehydrogenase ({{EC number|1.1.1.56}}) is an enzyme that catalyzes the chemical reaction

ribitol + NAD⁺ D-ribulose + NADH + H⁺

Thus, the two substrates of this enzyme are ribitol and NAD⁺, whereas its 3 products are D-ribulose, NADH, and H⁺.

This enzyme participates in pentose and glucuronate interconversions.

Nomenclature

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD⁺ or NADP⁺ as acceptor. The systematic name of this enzyme class is ribitol:NAD⁺ 2-oxidoreductase. Other names in common use include adonitol dehydrogenase, ribitol dehydrogenase A (wild type), ribitol dehydrogenase B (mutant enzyme with different properties), and ribitol dehydrogenase D (mutant enzyme with different properties).

References

{{cite journal | vauthors = Hollmann S, Touster O | title = The L-xylulose-xylitol enzyme and other polyol dehydrogenases of guinea pig liver mitochondria | journal = The Journal of Biological Chemistry | volume = 225 | issue = 1 | pages = 87-102 | date = Mar 1957 | pmid = 13416220 | authorlink2 = Oscar Touster }}
{{cite journal | vauthors = Nordlie RC, Fromm HJ | title = Ribitol dehydrogenase. II. Studies on the reaction mechanism | journal = The Journal of Biological Chemistry | volume = 234 | pages = 2523–31 | date = Oct 1959 | pmid = 14427582 }}
{{cite journal | vauthors = Wood WA, McDonough MJ, Jacobs LB | title = Rihitol and D-arabitol utilization by Aerobacter aerogenes | journal = The Journal of Biological Chemistry | volume = 236 | pages = 2190–5 | date = Aug 1961 | pmid = 13786517 }}

3 : EC 1.1.1|NADH-dependent enzymes|Enzymes of unknown structure

随便看

开放百科全书收录14589846条英语、德语、日语等多语种百科知识，基本涵盖了大多数领域的百科知识，是一部内容自由、开放的电子版国际百科全书。