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词条 Rokitamycin
释义

  1. External links

{{unreferenced|date=June 2016}}{{Drugbox
| Verifiedfields = changed
| verifiedrevid = 464383231
| IUPAC_name = (2S,3S,4R,6S)-6-{[(2R,3S,4R,5R,6S)-6-{[(4R,5S,6S,7R,9R,10R,11E,13E,16R)-4,10-dihydroxy-5-methoxy-9,16-dimethyl-2-oxo-7-(2-oxoethyl)-1-oxacyclohexadeca-11,13-dien-6-yl]oxy}-4-(dimethylamino)-5-hydroxy-2-methyloxan-3-yl]oxy}-2,4-dimethyl-4-propoxyoxan-3-yl butanoate
| image = rokitamycin.png
| tradename =
| Drugs.com = {{drugs.com|international|rokitamycin}}
| pregnancy_AU =
| pregnancy_US =
| legal_AU =
| legal_CA =
| legal_UK =
| legal_US =
| CAS_number_Ref = {{cascite|changed|??}}
| CAS_number = 74014-51-0
| ATC_prefix = J01
| ATC_suffix = FA12
| PubChem = 5282211
| DrugBank_Ref = {{drugbankcite|correct|drugbank}}
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
| ChemSpiderID = 4445397
| UNII_Ref = {{fdacite|correct|FDA}}
| UNII = ZPT03UEM0E
| ChEMBL_Ref = {{ebicite|changed|EBI}}
| ChEMBL = 1908350
| C=42 | H=71 | N=1 | O=14
| molecular_weight = 827.999 g/mol
| smiles = O=CC[C@H]3C[C@@H](C)[C@@H](O)/C=C/C=C/C[C@H](OC(=O)C[C@@H](O)[C@H](OC)[C@H]3O[C@@H]2O[C@@H]([C@@H](O[C@@H]1O[C@H]([C@H](OC(=O)CCC)[C@](OC(=O)CC)(C1)C)C)[C@H](N(C)C)[C@H]2O)C)C
| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
| StdInChI = 1S/C42H69NO15/c1-11-16-32(48)55-40-27(6)53-34(23-42(40,7)58-31(47)12-2)56-37-26(5)54-41(36(50)35(37)43(8)9)57-38-28(19-20-44)21-24(3)29(45)18-15-13-14-17-25(4)52-33(49)22-30(46)39(38)51-10/h13-15,18,20,24-30,34-41,45-46,50H,11-12,16-17,19,21-23H2,1-10H3/b14-13+,18-15+/t24-,25-,26-,27+,28+,29+,30-,34+,35-,36-,37-,38+,39+,40+,41+,42-/m1/s1
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
| StdInChIKey = VYWWNRMSAPEJLS-MDWYKHENSA-N
| melting_point = 116
| solubility = Insoluble in water; Very soluble in chloroform and methanol; Almost completely (>99.5%) in ethanol and acetonitrile.
}}

Rokitamycin is a macrolide antibiotic synthesized from strains of Streptomyces kitasatoensis.

{{Macrolides, lincosamides and streptogramins}}

External links

  • [https://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&term=Rokitamycin Recent Publications on Rokitamycin]
{{antibiotic-stub}}

1 : Macrolide antibiotics

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