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词条 Rubidium-82 chloride
释义

  1. References

  2. Further reading

{{Chembox
| IUPACName = Rubidium-82 chloride
| SystematicName = (82Rb)Rubidium chloride
|Section1={{Chembox Identifiers
| CASNo = 132486-03-4
| CASNo_Ref = {{cascite|correct|??}}
| PubChem = 71357
| ChemSpiderID = 64457
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
| KEGG = D05773
| KEGG_Ref = {{Keggcite|correct|kegg}}
| SMILES = [Cl-].[82Rb+]
| StdInChI = 1S/ClH.Rb/h1H;/q;+1/p-1/i;1-3
| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
| StdInChIKey = FGDZQCVHDSGLHJ-RYDPDVNUSA-M
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
|Section2={{Chembox Properties
| Formula = ClRb
| MolarMass = 117.371 g mol−1
|Section6={{Chembox Pharmacology
| ATCCode_prefix = V09
| ATCCode_suffix = GX04
}}
|Section8={{Chembox Related
| OtherCations = Caesium chloride
Lithium chloride
Potassium chloride
Rubidium chloride
Sodium chloride
}}Rubidium-82 chloride is a form of rubidium chloride containing a radioactive isotope of rubidium. It is marketed under the brand name Cardiogen-82 by Bracco Diagnostics for use in Myocardial perfusion imaging.[1] It is rapidly taken up by heart muscle cells, and therefore can be used to identify regions of heart muscle that are receiving poor blood flow in a technique called PET perfusion imaging.[2] The half-life of the rubidium-82 is only 1.27 minutes; it is normally produced at the place of use by rubidium generators.[3]

References

1. ^{{cite book | chapter-url = https://books.google.com/books?id=NS5ulJOG6wUC&pg=PA181 | chapter = Rubidium-82 Generator | title = Nuclear cardiology: the basics : how to set up and maintain a laboratory | isbn = 978-1-58829-924-6 | author1 = Th Wackers, Frans J | author2 = Bruni, Wendy | author3 = Zaret, Barry L | date = 2007-11-19}}
2. ^{{cite book| last1 = Ballinger | first1 = James R. | title = Integrating Cardiology for Nuclear Medicine Physicians | pages = 379–385 | year = 2009 | doi = 10.1007/978-3-540-78674-0_32 | chapter = PET Radiopharmaceuticals in Nuclear Cardiology: Current Status and Limitations | isbn = 978-3-540-78673-3}}
3. ^K. L. Gould et al. "Clinical feasibility of positron cardiac imaging without a cyclotron using generator-produced rubidium-82." Journal of the American College of Cardiology 1986;7:775–789.  

Further reading

  • {{cite book |url=https://books.google.com/books?id=Fn8vAQAAIAAJ&q=Cardiogen-82+stannic+oxide&dq=Cardiogen-82+stannic+oxide |title=Metallopharmaceuticals: Diagnosis and therapy |isbn=978-3-540-65308-0 |author1=Clarke, Michael J |author2=Sadler, P. J |date=1999-06-15}} (Note: only about 1/2 page on Rb-generator)
  • {{cite journal |last1=Alvarez-Diez |first1=T |title=Manufacture of strontium-82/rubidium-82 generators and quality control of rubidium-82 chloride for myocardial perfusion imaging in patients using positron emission tomography |journal=Applied Radiation and Isotopes |volume=50 |pages=1015–23 |year=1999 |doi=10.1016/S0969-8043(98)00170-5 |issue=6 |pmid=10355104 |last2=Dekemp |first2=R |last3=Beanlands |first3=R |last4=Vincent |first4=J}}
  • {{cite journal |editor1-last=Waters |editor1-first=S. L. |editor2-last=Curseys |editor2-first=B. M. |title=The Strontium-82/rubidium-82 generator |journal=International Journal of Radiation Applications and Instrumentation. Part A, Applied Radiation and Isotopes |volume=38 |issue=3 |pages=171–239 |year=1987 |url=http://www.sciencedirect.com/science/journal/08832889/38/3}}
{{Diagnostic radiopharmaceuticals}}{{DEFAULTSORT:Rubidium-82 Chloride}}{{Pharma-stub}}

5 : Radiocontrast agents|Rubidium compounds|Chlorides|Metal halides|Alkali metal chlorides

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