| 词条 | Ruzicka large-ring synthesis |
| 释义 |
The Ružička large-ring synthesis or Ružička reaction or Ružička cyclization is an organic reaction in which a dicarboxylic acid is converted to a cyclic ketone at high temperature and a suitable catalyst such as thorium oxide. The reaction is named after Lavoslav Ružička, who invented it in 1926.[1] The reaction has been applied in the synthesis of Exaltone, a synthetic Muscone. References1. ^{{cite journal| title = Zur Kenntnis des Kohlenstoffringes II. Synthese der carbocyclischen Ketone vom Zehner- bis zum Achtzehnerring|author1=L. Ruzicka |author2=M. Stoll |author3=H. Schinz | journal = Helvetica Chimica Acta| year = 1926| volume = 9| issue = 1| pages = 249–264| doi = 10.1002/hlca.19260090130 }} {{DEFAULTSORT:Ruzicka Large Ring Synthesis}} 2 : Substitution reactions|Name reactions |
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