| 词条 | S-Adenosyl-L-homocysteine |
| 释义 |
| Watchedfields = changed | verifiedrevid = 460764948 | Name=S-Adenosyl-L-homocysteine | ImageFile=S-Adenosyl-L-homocystein.svg | ImageSize= 300px | IUPACName= S-(5'-Deoxyadenos-5'-yl)-L-homocysteine | OtherNames=AdoHcy, 2-S-adenosyl-L-homocysteine, 5'-S-(3-Amino-3-carboxypropyl)-5'-thioadenosine S-adenosylhomocysteine, SAH |Section1={{Chembox Identifiers | IUPHAR_ligand = 5265 | CASNo_Ref = {{cascite|correct|CAS}} | CASNo=979-92-0 | ChEMBL_Ref = {{ebicite|correct|EBI}} | ChEMBL = 418052 | PubChem = 439155 | ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} | ChemSpiderID = 388301 | SMILES = O=C(O)[C@@H](N)CCSC[C@H]3O[C@@H](n2cnc1c(ncnc12)N)[C@H](O)[C@@H]3O | InChI = 1/C14H20N6O5S/c15-6(14(23)24)1-2-26-3-7-9(21)10(22)13(25-7)20-5-19-8-11(16)17-4-18-12(8)20/h4-7,9-10,13,21-22H,1-3,15H2,(H,23,24)(H2,16,17,18)/t6-,7+,9+,10+,13+/m0/s1 | InChIKey = ZJUKTBDSGOFHSH-WFMPWKQPBX | StdInChI_Ref = {{stdinchicite|correct|chemspider}} | StdInChI = 1S/C14H20N6O5S/c15-6(14(23)24)1-2-26-3-7-9(21)10(22)13(25-7)20-5-19-8-11(16)17-4-18-12(8)20/h4-7,9-10,13,21-22H,1-3,15H2,(H,23,24)(H2,16,17,18)/t6-,7+,9+,10+,13+/m0/s1 | StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} | StdInChIKey = ZJUKTBDSGOFHSH-WFMPWKQPSA-N | MeSHName=S-Adenosylhomocysteine | ChEBI_Ref = {{ebicite|correct|EBI}} | ChEBI=16680 | KEGG_Ref = {{keggcite|correct|kegg}} | KEGG=C00021 |Section2={{Chembox Properties | Formula= | C=14 | H=20 | N=6 | O=5 | S=1 | MolarMass=384.412 | Appearance= | Density= | MeltingPt= | BoilingPt= | Solubility= |Section3={{Chembox Hazards | MainHazards= | FlashPt= | AutoignitionPt = }}S-Adenosyl-L-homocysteine (SAH) is an amino acid derivative used in several metabolic pathways in most organisms. It is an intermediate in the synthesis of cysteine and adenosine.[1] SAH is formed by the demethylation of S-adenosyl-L-methionine and is converted to homocysteine and adenosine by adenosylhomocysteinase. References1. ^{{cite journal|url=https://academic.oup.com/jn/article/132/8/2361S/4687579|doi=10.1093/jn/132.8.2361S|pmid=12163693|title=Elevation in S-Adenosylhomocysteine and DNA Hypomethylation: Potential Epigenetic Mechanism for Homocysteine-Related Pathology|journal=The Journal of Nutrition|volume=132|issue=8|pages=2361S–2366S|year=2002|last1=James|first1=S. Jill|last2=Melnyk|first2=Stepan|last3=Pogribna|first3=Marta|last4=Pogribny|first4=Igor P|last5=Caudill|first5=Marie A}} External links
3 : Nucleosides|Purines|Amino acid derivatives |
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