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词条 Emil Fischer
释义

  1. Early years

  2. Research

  3. Honours, awards, and legacy

  4. References

  5. External links

{{otherpeople}}{{Refimprove|date=October 2017}}{{Use dmy dates|date=October 2016}}{{Infobox scientist
| name = Hermann Emil Fischer
| image =Убеншвуаншвышь.jpg
| caption = Hermann Emil Fischer
|birth_name=Hermann Emil Louis Fischer
| birth_date = {{birth date|1852|10|9|df=y}}
| birth_place = Euskirchen, Rhine Province
| nationality = Germany
| death_date = {{death date and age|df=yes|1919|7|15|1852|10|9}}
| death_place = Berlin, Germany
| death_cause =
| field = Chemistry
| alma_mater = University of Bonn
University of Strasbourg
| work_institution = University of Munich (1875–81)
University of Erlangen (1881–88)
University of Würzburg (1888–92)
University of Berlin (1892–1919)
| doctoral_advisor = Adolf von Baeyer{{cn|date=August 2017}}
| doctoral_students = Alfred Stock
Otto Diels
Otto Ruff
Walter A. Jacobs
Ludwig Knorr
Oskar Piloty
Julius Tafel
| known_for = Study of sugars & purines
| prizes = {{Plainlist|
  • Davy Medal {{small|(1890)}}
  • ForMemRS {{small|(1899)}}[1]
  • Nobel Prize in Chemistry {{small|(1902)}}
  • Faraday Lectureship Prize {{small|(1907)}}
  • Elliott Cresson Medal {{small|(1913)}}}}

}}Hermann Emil Louis Fischer FRS FRSE FCS (9 October 1852 – 15 July 1919) was a German chemist and 1902 recipient of the Nobel Prize in Chemistry. He discovered the Fischer esterification. He also developed the Fischer projection, a symbolic way of drawing asymmetric carbon atoms. He never used his first given name, and was known throughout his life simply as Emil Fischer.[2][3][4][5]

Early years

Fischer was born in Euskirchen, near Cologne, the son of Laurenz Fischer, a businessman, and his wife Julie Poensgen. After graduating he wished to study natural sciences, but his father compelled him to work in the family business until determining that his son was unsuitable. Fischer then attended the University of Bonn in 1871, but switched to the University of Strasbourg in 1872.[6] He earned his doctorate in 1874 under Adolf von Baeyer[6] with his study of phthaleins and was appointed to a position at the university.

Research

Fischer is noted for his work on sugars: among other work, the organic synthesis of D-(+)-glucose[7] and purines (including the first synthesis of caffeine).

Fischer was also instrumental in the discovery of barbiturates, a class of sedative drugs used for insomnia, epilepsy, anxiety, and anesthesia. Along with the physician Josef von Mering, he helped to launch the first barbiturate sedative, barbital, in 1904.[8]

Honours, awards, and legacy

In 1897 he put forward the idea to create the International Atomic Weights Commission. Fischer was elected a Foreign Member of the Royal Society (ForMemRS) in 1899.[1]

Many names of chemical reactions and concepts are named after him:

{{div col|colwidth=35em}}
  • Fischer indole synthesis
  • Fischer projection
  • Fischer oxazole synthesis
  • Fischer peptide synthesis
  • Fischer phenylhydrazine and oxazone reaction
  • Fischer reduction
  • Fischer–Speier esterification
  • Fischer glycosidation
{{div col end}}

(Fischer–Tropsch process is named after Franz Emil Fischer a chemist who was no relation, head of the Max Planck Institute for Coal Research in Muelheim.)

References

1. ^{{cite web |archiveurl=https://web.archive.org/web/20150316060617/https://royalsociety.org/about-us/fellowship/fellows/ |archivedate=2015-03-16 |url=https://royalsociety.org/about-us/fellowship/fellows/ |publisher=Royal Society |location=London |title=Fellows of the Royal Society}}
2. ^{{cite journal|title= Emil Fischer – Unequalled Classicist, Master of Organic Chemistry Research, and Inspired Trailblazer of Biological Chemistry| author= Horst Kunz| journal= Angewandte Chemie International Edition |volume = 41| pages= 4439–4451 |doi=10.1002/1521-3773(20021202)41:23<4439::AID-ANIE4439>3.0.CO;2-6|year= 2002|issue= 23| pmid=12458504}}
3. ^{{Cite journal| doi = 10.1002/ange.19921041204| title = Emil Fischers Beweis der Konfiguration von Zuckern: eine Würdigung nach hundert Jahren| year = 1992| last1 = Lichtenthaler | first1 = F. W.| journal = Angewandte Chemie| volume = 104| issue = 12| pages = 1577–1593 }}
4. ^{{cite journal|last=Forster|first=Martin Onslow|title=Emil Fischer memorial lecture|journal=Journal of the Chemical Society, Transactions|date=1 January 1920|volume=117|pages=1157–1201|doi=10.1039/CT9201701157}}
5. ^Biography Biography of Fischer from Nobelprize.org website
6. ^{{DSB|first= Farber|last= Eduard|title= Fischer, Emil Hermann|volume= 5|pages= 1–5}}
7. ^{{cite journal | title = Synthese des Traubenzuckers | pages = 799–805 | first = Emil | last = Fischer | doi = 10.1002/cber.189002301126 | journal = Berichte der Deutschen Chemischen Gesellschaft | year = 1890 | volume = 23}}
8. ^{{cite journal |last1=López-Muñoz |first1=Francisco |last2=Ucha-Udabe |first2=Ronaldo |last3=Alamo |first3=Cecilio |date=2005 |title=The history of barbiturates a century after their clinical introduction |pmc=2424120 |journal=Neuropsychiatric Disease and Treatment |volume=1 |issue=4 |pages=329–43 |pmid=18568113 }}

External links

  • Nobel Lecture Syntheses in the Purine and Sugar Group from Nobelprize.org website
  • [https://books.google.com/books?id=5OcIAAAAIAAJ&pg=PA238 Eminent Chemists of Our Time] By Benjamin Harrow pages 216–239, published 1920 by Von Nostrand Company at books.google.com.
  • Guide to the Emil Fischer Papers at The Bancroft Library
  • [https://books.google.com/books?id=fraaVP7NeOEC&pg=PA149 Text-book of Physiological Chemistry in Thirty Lectures] by Emil Abderhalden, translated by William Thomas Hall and George Defren; published 1908 by Wiley Company, has many technical references to Fischer's work in Chemistry.
  • [https://books.google.com/books?id=j9YAAAAAYAAJ&pg=PA189 American Journal of Diseases of Children 1911] volume 2 by the American Medical Association also refers to Fischer's work.
  • [https://books.google.com/books?id=JvoIAAAAIAAJ&pg=PA708 An Introduction to the History of Medicine: With Medical Chronology] by Fielding Hudson Garrison, page 708 refers to Fischer and Merings discovery of the drugs veronal(1904) and proponal(1905), published 1921 by Saunders Company.
  • [https://books.google.com/books?id=8URLAAAAMAAJ&pg=PA438 1914 Year Book of the American Pharmaceutical Association], page 438 abstracts Fischer and Strauss's work on Phenol-Glucosides – Synthetic Production from Berlin d.D Chem. Germany, page 45(1912) No. 12.
  • {{Wikisource-inline|list=
    • {{Cite NIE|wstitle=Fischer, Emil|year=1905|short=x |noicon=x}}
    • {{Cite EB1911|wstitle=Fischer, Emil|short=x |noicon=x}}
    • {{Cite Americana|wstitle=Fischer, Emil|year=1920|short=x |noicon=x}}

}}{{Nobel Prize in Chemistry Laureates 1901–1925}}{{Authority control}}{{DEFAULTSORT:Fischer, Hermann Emil}}

21 : Hermann Emil Fischer|1852 births|1919 deaths|19th-century German chemists|20th-century German chemists|People from Euskirchen|Carbohydrate chemistry|German biochemists|German Nobel laureates|Nobel laureates in Chemistry|Organic chemists|Stereochemists|University of Erlangen-Nuremberg faculty|People from the Rhine Province|Humboldt University of Berlin faculty|Scientists who committed suicide|Suicides in Germany|University of Bonn alumni|Foreign Members of the Royal Society|Members of the Bavarian Maximilian Order for Science and Art|Recipients of the Pour le Mérite (civil class)

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