SFE may refer to:

• Sales force effectiveness
• Scottish Financial Enterprise
• Scouts for Equality
• Sigma Phi Epsilon
• Shannon-Fano-Elias coding, a lossless data compression algorithm
• Supercritical fluid extraction
• Sydney Futures Exchange, now merged with the Australian Stock Exchange to become the Australian Securities Exchange
• Stacking-fault energy
• Star-formation efficiency
• SparkFun Electronics
• Secure function evaluation
• Spec-Files-Extra, a way to build common packages for OpenSolaris or OpenIndiana
• Supplier-furnished equipment
• Surface free energy
• The Encyclopedia of Science Fiction

• Service request management
• Service revolver
• Service rifle
• Service scan
• Service science, management and engineering
• Services cricket team
• Services for unix
• Services for UNIX
• Services hospital
• Services Hospital
• Services innovation
• Services in Romania
• Services Institute of Medical Sciences
• Services Integration Maturity Model
• Services Menu
• Services menu
• Service Squadron
• Services Reconnaissance Department
• Services: Science, Management, and Engineering
• Services Selection Board
• Service Star
• Service stations
• Services trade
• Services trade statistics
• Service switching point