词条 | Signal-recognition-particle GTPase |
释义 |
| Name = Signal-recognition-particle GTPase | EC_number = 3.6.5.4 | CAS_number = | IUBMB_EC_number = 3/6/5/4 | GO_code = | image = | width = | caption = }}Signal-recognition-particle GTPase ({{EC number|3.6.5.4}}) is an enzyme with systematic name GTP phosphohydrolase (protein-synthesis-assisting).[1][2][3][4] This enzyme catalyses the following chemical reaction GTP + H2O GDP + phosphate Enzyme activity is associated with the signal-recognition particle. References1. ^{{cite journal | title = The signal recognition particle receptor mediates the GTP-dependent displacement of SRP from the signal sequence of the nascent polypeptide |author1 = Connolly, T. |author2 =Gilmore, R. |journal = Cell |date = 1989 |volume = 57 |pages = 599-610 |pmid = 2541918 |issue=4 |doi=10.1016/0092-8674(89)90129-3}} 2. ^{{cite journal | title = Requirement of GTP hydrolysis for dissociation of the signal recognition particle from its receptor |author1 = Connolly, T. |author2 =Rapiejko, P.J. |author3 =Gilmore, R. |journal = Science |date = 1991 |volume = 252 |pages = 1171-1173 |pmid = 1851576 |doi=10.1126/science.252.5009.1171 |issue=5009}} 3. ^{{cite journal | title = GTP binding and hydrolysis by the signal recognition particle during initiation of protein translocation |author1 = Miller, J.D. |author2 =Wilhelm, H. |author3 =Gierasch, L. |author4 =Gilmore, R. |author5 =Walter, P. |journal = Nature |date = 1993 |volume = 366 |pages = 351-354 |pmid = 8247130 |doi=10.1038/366351a0 |issue=6453}} 4. ^{{cite journal | title = Structure of the conserved GTPase domain of the signal recognition particle |author1 = Freymann, D.M. |author2 =Keenan, R.J. |author3 =Stroud, R.M. |author4 =Walter, P. |journal = Nature |date = 1997 |volume = 385 |pages = 361-364 |pmid = 9002524 |doi=10.1038/385361a0 |issue=6614}} See also
External links
1 : EC 3.6.5 |
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