| 词条 | Small nucleolar RNA SNORD14 |
| 释义 |
| Name = Small nucleolar RNA SNORD14 | image = RF00016.jpg | width = | caption = Predicted secondary structure and sequence conservation of SNORD14 | Symbol = SNORD14 | AltSymbols = U14 | Rfam = RF00016 | miRBase = | miRBase_family = | RNA_type = Gene; snRNA; snoRNA; CD-box | Tax_domain = Eukaryota | GO = {{GO|0006396}} {{GO|0005730}} | SO = {{SO|0000593}} | CAS_number = | EntrezGene = | HGNCid = | OMIM = | PDB = | RefSeq = | Chromosome = | Arm = | Band = | LocusSupplementaryData = }} U14 small nucleolar RNA (U14 snoRNA) is a non-coding RNA required for early cleavages of eukaryotic precursor rRNAs. In yeasts, this molecule possess a stem-loop region (known as the Y-domain) which is essential for function. A similar structure, but with a different consensus sequence, is found in plants, but is absent in vertebrates.[1] In human there are two closely related copies called SNORD14A and SNORD14B that are expressed from the intron of their host gene ribosomal protein Rps13. References1. ^{{cite journal | vauthors = Samarsky DA, Schneider GS, Fournier MJ | title = An essential domain in Saccharomyces cerevisiae U14 snoRNA is absent in vertebrates, but conserved in other yeasts | journal = Nucleic Acids Research | volume = 24 | issue = 11 | pages = 2059–66 | date = June 1996 | pmid = 8668536 | pmc = 145897 | doi = 10.1093/nar/24.11.2059 }} External links
1 : Small nuclear RNA |
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