词条 | Small nucleolar RNA SNORD21 |
释义 |
| Name = Small nucleolar RNA SNORD21 | image = RF00068.jpg | width = | caption = Predicted secondary structure and sequence conservation of SNORD21 | Symbol = SNORD21 | AltSymbols = U21 | Rfam = RF00068 | miRBase = | miRBase_family = | RNA_type = Gene; snRNA; snoRNA; CD-box | Tax_domain = Eukaryota | GO = {{GO|0006396}} {{GO|0005730}} | SO = {{SO|0000593}} | CAS_number = | EntrezGene = | HGNCid = | OMIM = | PDB = | RefSeq = | Chromosome = | Arm = | Band = | LocusSupplementaryData = }} U21 is a member of the C/D class of snoRNA which contain the C (UGAUGA) and D (CUGA) box motifs. U21 is encoded within an intron of the gene for ribosomal protein L5 in mammals,[1] but within introns of the ADP ribosylation factor gene in Drosophila.[2] U21 snoRNA has a 13 nucleotide region of complementarity with an invariant region of eukaryotic 28S ribosomal RNA. References1. ^{{cite journal | last = Qu | first = LH |author2=Nicoloso M |author3=Michot B |author4=Azum MC |author5=Caizergues-Ferrer M |author6=Renalier MH |author7=Bachellerie JP | year = 1994 | title = U21, a novel small nucleolar RNA with a 13 nt. complementarity to 28S rRNA, is encoded in an intron of ribosomal protein L5 gene in chicken and mammals | journal = Nucleic Acids Res | volume = 22 | pages = 4073–4081 | pmid = 7937132 | doi = 10.1093/nar/22.20.4073 | issue = 20 | pmc = 331892}} 2. ^[2] {{cite journal | last = Renalier | first = MH |author2=Nicoloso M |author3=Qu LH |author4=Bachellerie JP | year = 1996 | title = SnoRNA U21 is also intron-encoded in Drosophila melanogaster but in a different host-gene as compared to warm-blooded vertebrates | journal = FEBS Lett | volume = 379 | pages = 212–216 | pmid = 8603691 | doi = 10.1016/0014-5793(95)01511-6 | issue = 3}} External links
1 : Small nuclear RNA |
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