| 词条 | Small nucleolar RNA Z161/Z228 |
| 释义 |
| Name = Small nucleolar RNA Z161/Z228 | image = RF00328.jpg | width = | caption = Predicted secondary structure and sequence conservation of snoZ161_228 | Symbol = snoZ161_228 | AltSymbols = snoZ161 | Rfam = RF00328 | miRBase = | miRBase_family = | RNA_type = Gene; snRNA; snoRNA; CD-box | Tax_domain = Eukaryota | GO = {{GO|0006396}} {{GO|0005730}} | SO = {{SO|0000593}} | CAS_number = | EntrezGene = | HGNCid = | OMIM = | PDB = | RefSeq = | Chromosome = | Arm = | Band = | LocusSupplementaryData = }} Small nucleolar RNA Z161 (homologous to snoRNA Z228) is a non-coding RNA (ncRNA) molecule which functions in the modification of other small nuclear RNAs (snRNAs). This type of modifying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA. snoRNA Z161 belongs to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs.[1][2] Plant snoRNA Z161 was identified in a screen of Oryza sativa.[3] References1. ^{{Cite journal | last1 = Galardi | first1 = S.| last2 = Fatica | first2 = A.| last3 = Bachi | first3 = A.| last4 = Scaloni | first4 = A.| last5 = Presutti | first5 = C.| last6 = Bozzoni | first6 = I.| doi = 10.1128/MCB.22.19.6663-6668.2002 | title = Purified Box C/D snoRNPs Are Able to Reproduce Site-Specific 2'-O-Methylation of Target RNA in Vitro | journal = Molecular and Cellular Biology| volume = 22 | issue = 19 | pages = 6663–6668 | date=October 2002 | pmid = 12215523| pmc = 134041}} 2. ^{{cite journal | last = Kiss | first = T | year = 2002 | title = Small nucleolar RNAs: an abundant group of noncoding RNAs with diverse cellular functions | journal = Cell | volume = 109 | pages = 145–148 | pmid = 12007400 | doi = 10.1016/S0092-8674(02)00718-3 | issue = 2}} 3. ^{{cite journal |vauthors=Chen CL, Liang D, Zhou H, Zhuo M, Chen YQ, Qu LH | title = The high diversity of snoRNAs in plants: identification and comparative study of 120 snoRNA genes from Oryza sativa | journal = Nucleic Acids Res. | volume = 31 | issue = 10 | pages = 2601–13 | year = 2003 | pmid = 12736310 | doi = 10.1093/nar/gkg373 | pmc = 156054 }} External links
1 : Small nuclear RNA |
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