| 词条 | Small nucleolar RNA Z199 |
| 释义 |
| Name = Small nucleolar RNA Z199 | image = RF00200.jpg | width = | caption = Predicted secondary structure and sequence conservation of snoZ199 | Symbol = snoZ199 | AltSymbols = | Rfam = RF00200 | miRBase = | miRBase_family = | RNA_type = Gene; snRNA; snoRNA; CD-box | Tax_domain = Eukaryota | GO = {{GO|0006396}} {{GO|0005730}} | SO = {{SO|0000593}} | CAS_number = | EntrezGene = | HGNCid = | OMIM = | PDB = | RefSeq = | Chromosome = | Arm = | Band = | LocusSupplementaryData = }} snoRNA Z199 is a non-coding RNA (ncRNA) molecule which functions in the biogenesis (modification) of other small nuclear RNAs (snRNAs). This type of modifying RNA is located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA. snoRNA Z199 is a member of the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs.[1] snoZ199 is predicted to be a methylation guide for sites on 18S and 25S ribosomal RNA (rRNA). Oryza sativa snoZ199 is reported to be homologous to Arabidopsis thaliana snoR13.[2] References1. ^{{Cite journal | last1 = Galardi | first1 = S.| last2 = Fatica | first2 = A.| last3 = Bachi | first3 = A.| last4 = Scaloni | first4 = A.| last5 = Presutti | first5 = C.| last6 = Bozzoni | first6 = I.| doi = 10.1128/MCB.22.19.6663-6668.2002 | title = Purified Box C/D snoRNPs Are Able to Reproduce Site-Specific 2'-O-Methylation of Target RNA in Vitro | journal = Molecular and Cellular Biology| volume = 22 | issue = 19 | pages = 6663–6668 | date=October 2002 | pmid = 12215523| pmc = 134041}} 2. ^{{cite journal | last = Chen | first = CL |author2=Liang D |author3=Zhou H |author4=Zhuo M |author5=Chen YQ |author6=Qu LH | year = 2003 | title = The high diversity of snoRNAs in plants: identification and comparative study of 120 snoRNA genes from Oryza sativa | journal = Nucleic Acids Res | volume = 31 | pages = 2601–2613 | pmid = 12736310 | doi = 10.1093/nar/gkg373 | issue = 10 | pmc = 156054}} External links
1 : Small nuclear RNA |
| 随便看 |
|
开放百科全书收录14589846条英语、德语、日语等多语种百科知识，基本涵盖了大多数领域的百科知识，是一部内容自由、开放的电子版国际百科全书。