| 词条 | Small nucleolar RNA Z223 |
| 释义 |
| Name = Small nucleolar RNA Z223 | image = RF00135.jpg | width = | caption = Predicted secondary structure and sequence conservation of snoZ223 | Symbol = snoZ223 | AltSymbols = | Rfam = RF00135 | miRBase = | miRBase_family = | RNA_type = Gene; snRNA; snoRNA; CD-box | Tax_domain = Eukaryota | GO = {{GO|0006396}} {{GO|0005730}} | SO = {{SO|0000593}} | CAS_number = | EntrezGene = | HGNCid = | OMIM = | PDB = | RefSeq = | Chromosome = | Arm = | Band = | LocusSupplementaryData = }} Small nucleolar RNA Z223 is a non-coding RNA (ncRNA) molecule which functions in the modification of other small nuclear RNAs (snRNAs). This type of modifying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA. snoRNA Z223 belongs to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs.[1] Plant snoRNA Z223 was identified in a screen of Arabidopsis thaliana.[2] References1. ^{{Cite journal | last1 = Galardi | first1 = S.| last2 = Fatica | first2 = A.| last3 = Bachi | first3 = A.| last4 = Scaloni | first4 = A.| last5 = Presutti | first5 = C.| last6 = Bozzoni | first6 = I.| doi = 10.1128/MCB.22.19.6663-6668.2002 | title = Purified Box C/D snoRNPs Are Able to Reproduce Site-Specific 2'-O-Methylation of Target RNA in Vitro | journal = Molecular and Cellular Biology| volume = 22 | issue = 19 | pages = 6663–6668 | date=October 2002 | pmid = 12215523| pmc = 134041}} 2. ^{{Cite journal | last1 = Marker | first1 = C.| last2 = Zemann | first2 = A.| last3 = Terhörst | first3 = T.| last4 = Kiefmann | first4 = M.| last5 = Kastenmayer | first5 = J. P.| last6 = Green | first6 = P.| last7 = Bachellerie | first7 = J. P.| last8 = Brosius | first8 = J. R.| last9 = Hüttenhofer | first9 = A.| doi = 10.1016/S0960-9822(02)01304-0 | title = Experimental RNomics: identification of 140 candidates for small non-messenger RNAs in the plant Arabidopsis thaliana| journal = Current Biology | volume = 12 | issue = 23 | pages = 2002–2013 | date = 10 December 2002| pmid = 12477388| pmc = }} External links
1 : Small nuclear RNA |
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