词条 | S-Nitroso-N-acetylpenicillamine |
释义 |
| Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 464384996 | Name = S-Nitroso-N-acetylpenicillamine | ImageFile = S-Nitroso-N-acetylpenicillamine.svg | ImageSize = | ImageAlt = Skeletal formula of SNAP | ImageFile1 = SNAP-3D-balls.png | ImageSize1 = | ImageAlt1 = Ball-and-stick model of SNAP | IUPACName = S-Nitroso-N-acetylpenicillamine | OtherNames = N-Acetyl-3-(nitrosothio)-DL-valine S-Nitroso-N-acetylpenicillamine |Section1={{Chembox Identifiers | Abbreviations = SNAP | ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} | ChemSpiderID = 5036251 | InChI = 1/C7H12N2O4S/c1-4(10)8-5(6(11)12)7(2,3)14-9-13/h5H,1-3H3,(H,8,10)(H,11,12)/t5-/m0/s1 | InChIKey = ZIIQCSMRQKCOCT-YFKPBYRVBE | SMILES = O=C(N[C@@H](C(=O)O)C(SN=O)(C)C)C | ChEMBL_Ref = {{ebicite|correct|EBI}} | ChEMBL = 73188 | ChEBI_Ref = {{ebicite|changed|EBI}} | ChEBI = 77702 | StdInChI_Ref = {{stdinchicite|correct|chemspider}} | StdInChI = 1S/C7H12N2O4S/c1-4(10)8-5(6(11)12)7(2,3)14-9-13/h5H,1-3H3,(H,8,10)(H,11,12)/t5-/m0/s1 | StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} | StdInChIKey = ZIIQCSMRQKCOCT-YFKPBYRVSA-N | CASNo_Ref = {{cascite|changed|??}} | CASNo = 67776-06-1 | EINECS = | PubChem = 6603945 | RTECS = |Section2={{Chembox Properties | Formula = C7H12N2O4S | MolarMass = 220.25 g/mol | Appearance = | Density = | MeltingPt = | BoilingPt = | Solubility = | SolubleOther = | Solvent = | pKa = |Section7={{Chembox Hazards | EUClass = | MainHazards = | NFPA-H = | NFPA-F = | NFPA-R = | NFPA-S = | RPhrases = {{R36/37/38}} | SPhrases = {{S26}} {{S36}} | RSPhrases = | FlashPt = | PEL = }} S-Nitroso-N-acetylpenicillamine (SNAP) is the chemical compound with the formula ONSC(CH3)2CH(NHAc)CO2H. SNAP is an S-nitrosothiol and is used as a model for the general class of S-nitrosothiols which have received much attention in biochemistry because nitric oxide and some organic nitroso derivatives serve as signaling molecules in living systems, especially related to vasodilation.[1] SNAP is derived from the amino acid penicillamine. S-Nitrosoglutathione is a related agent. References1. ^{{ cite journal |author1=Zhang Y. |author2=Hogg, N. | title = S-Nitrosothiols: Cellular Formation and Transport | journal = Free Radical Biology and Medicine | year = 2005 | volume = 38 | issue = 7 | pages = 831–838 | pmid = 15749378 | doi = 10.1016/j.freeradbiomed.2004.12.016 }} {{Nitric oxide signaling}}{{DEFAULTSORT:Nitroso-N-acetylpenicillamine, S-}} 2 : Sulfur compounds|Nitroso compounds |
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