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词条 S-Nitroso-N-acetylpenicillamine
释义

  1. References

{{DISPLAYTITLE:S-Nitroso-N-acetylpenicillamine}}{{Chembox
| Verifiedfields = changed
| Watchedfields = changed
| verifiedrevid = 464384996
| Name = S-Nitroso-N-acetylpenicillamine
| ImageFile = S-Nitroso-N-acetylpenicillamine.svg
| ImageSize =
| ImageAlt = Skeletal formula of SNAP
| ImageFile1 = SNAP-3D-balls.png
| ImageSize1 =
| ImageAlt1 = Ball-and-stick model of SNAP
| IUPACName = S-Nitroso-N-acetylpenicillamine
| OtherNames = N-Acetyl-3-(nitrosothio)-DL-valine
S-Nitroso-N-acetylpenicillamine
|Section1={{Chembox Identifiers
| Abbreviations = SNAP
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
| ChemSpiderID = 5036251
| InChI = 1/C7H12N2O4S/c1-4(10)8-5(6(11)12)7(2,3)14-9-13/h5H,1-3H3,(H,8,10)(H,11,12)/t5-/m0/s1
| InChIKey = ZIIQCSMRQKCOCT-YFKPBYRVBE
| SMILES = O=C(N[C@@H](C(=O)O)C(SN=O)(C)C)C
| ChEMBL_Ref = {{ebicite|correct|EBI}}
| ChEMBL = 73188
| ChEBI_Ref = {{ebicite|changed|EBI}}
| ChEBI = 77702
| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
| StdInChI = 1S/C7H12N2O4S/c1-4(10)8-5(6(11)12)7(2,3)14-9-13/h5H,1-3H3,(H,8,10)(H,11,12)/t5-/m0/s1
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
| StdInChIKey = ZIIQCSMRQKCOCT-YFKPBYRVSA-N
| CASNo_Ref = {{cascite|changed|??}}
| CASNo = 67776-06-1
| EINECS =
| PubChem = 6603945
| RTECS =
|Section2={{Chembox Properties
| Formula = C7H12N2O4S
| MolarMass = 220.25 g/mol
| Appearance =
| Density =
| MeltingPt =
| BoilingPt =
| Solubility =
| SolubleOther =
| Solvent =
| pKa =
|Section7={{Chembox Hazards
| EUClass =
| MainHazards =
| NFPA-H =
| NFPA-F =
| NFPA-R =
| NFPA-S =
| RPhrases = {{R36/37/38}}
| SPhrases = {{S26}} {{S36}}
| RSPhrases =
| FlashPt =
| PEL =
}}

S-Nitroso-N-acetylpenicillamine (SNAP) is the chemical compound with the formula ONSC(CH3)2CH(NHAc)CO2H.

SNAP is an S-nitrosothiol and is used as a model for the general class of S-nitrosothiols which have received much attention in biochemistry because nitric oxide and some organic nitroso derivatives serve as signaling molecules in living systems, especially related to vasodilation.[1]

SNAP is derived from the amino acid penicillamine. S-Nitrosoglutathione is a related agent.

References

1. ^{{ cite journal |author1=Zhang Y. |author2=Hogg, N. | title = S-Nitrosothiols: Cellular Formation and Transport | journal = Free Radical Biology and Medicine | year = 2005 | volume = 38 | issue = 7 | pages = 831–838 | pmid = 15749378 | doi = 10.1016/j.freeradbiomed.2004.12.016 }}
{{Nitric oxide signaling}}{{DEFAULTSORT:Nitroso-N-acetylpenicillamine, S-}}

2 : Sulfur compounds|Nitroso compounds

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