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词条 Sporadic hemiplegic migraine
释义

  1. Presentation

  2. Cause

  3. Diagnosis

     Investigations  Differential diagnosis 

  4. Treatment

  5. Epidemiology

  6. References

  7. External links

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}}Sporadic hemiplegic migraine (SHM) is a form of hemiplegic migraine headache isolated cases of which are observed.[1] It is a rare disease. It is considered to be a separate type of migraine.[2]

Presentation

Sporadic hemiplegic migraine (SHM) has clinical symptoms identical to familial hemiplegic migraine (FHM) and distinct from migraine with aura. By definition the neurodeficits are supposed to be reversible. However, some cases with permanent neurological deficits have also been noted.[3]

Cause

{{Empty section|date=August 2017}}

Diagnosis

Diagnostic criteria require motor symptoms and at least one visual, sensory, or speech symptom, resembling basilar migraine.[4] They may also be associated with cerebellar signs.[5]

Investigations

MRI features can be suggestive of cortical hyper intensity and edema.[6]

Differential diagnosis

Differential diagnoses can be:[4]

  • Todd's paresis
  • Stroke
  • Systemic lupus erythematosus
  • Metabolic disorders
  • Inherited disorders such as mitochondrial myopathy
  • Functional neurological disorder

Treatment

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Epidemiology

Prevalence is estimated to be 0.005%.[7] The age of onset has been found to be under 15 years in 40% of cases while it is between 10 and 14 years in one third of the cases. Females outnumber males, 4 to 1. Only 3% have attacks after age 52.[2]

References

1. ^{{cite web|title=sporadic hemiplegic migraine|url=https://ghr.nlm.nih.gov/condition/sporadic-hemiplegic-migraine|website=Genetics Home Reference|publisher=Genetics Home Reference|accessdate=19 June 2017|language=en}}
2. ^{{cite journal|last1=Thomsen|first1=LL|last2=Ostergaard|first2=E|last3=Olesen|first3=J|last4=Russell|first4=MB|title=Evidence for a separate type of migraine with aura: sporadic hemiplegic migraine.|journal=Neurology|date=25 February 2003|volume=60|issue=4|pages=595-601|doi=10.1212/01.WNL.0000046524.25369.7D|pmid=12601098}}
3. ^{{cite journal|last1=Schwedt|first1=Todd J.|last2=Zhou|first2=Jiying|last3=Dodick|first3=David W.|title=Sporadic Hemiplegic Migraine With Permanent Neurological Deficits|journal=Headache: The Journal of Head and Face Pain|date=January 2014|volume=54|issue=1|pages=163–166|doi=10.1111/head.12232|pmc=4220590|pmid=24117121}}
4. ^{{cite journal|last1=Millichap|first1=J Gordon|title=Sporadic Hemiplegic Migraine: A Separate Entity|journal=Pediatric Neurology Briefs|date=1 April 2003|volume=17|issue=4|pages=32|doi=10.15844/pedneurbriefs-17-4-8}}
5. ^{{cite journal|last1=Vahedi|first1=K|last2=Denier|first2=C|last3=Ducros|first3=A|last4=Bousson|first4=V|last5=Levy|first5=C|last6=Chabriat|first6=H|last7=Haguenau|first7=M|last8=Tournier-Lasserve|first8=E|last9=Bousser|first9=MG|title=CACNA1A gene de novo mutation causing hemiplegic migraine, coma, and cerebellar atrophy.|journal=Neurology|date=10 October 2000|volume=55|issue=7|pages=1040-2|doi=10.1212/WNL.55.7.1040|pmid=11061267}}
6. ^{{cite journal|last1=Bhatia|first1=Harsha|last2=Babtain|first2=Fawzi|title=Sporadic Hemiplegic Migraine with Seizures and Transient MRI Abnormalities|journal=Case Reports in Neurological Medicine|date=2011|volume=2011|pages=1–4|doi=10.1155/2011/258372}}
7. ^{{cite journal|last1=Thomsen|first1=LL|last2=Olesen|first2=J|title=Sporadic Hemiplegic Migraine|journal=Cephalalgia|date=December 2004|volume=24|issue=12|pages=1016–1023|doi=10.1111/j.1468-2982.2004.00788.x}}

External links

{{Medical resources
| ICD10 = G43.1
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| OMIM = 141500
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}}{{CNS diseases of the nervous system}}{{Headache}}

3 : Channelopathies|Headaches|Rare diseases

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