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词条 Study of Tamoxifen and Raloxifene
释义

  1. Research

  2. References

  3. External links

The Study of Tamoxifen and Raloxifene (STAR) is a clinical trial designed determine how the drug raloxifene compares with the drug tamoxifen in reducing the incidence of breast cancer in women who are at increased risk of the disease.[1]

Research

One of the largest breast cancer prevention studies ever,[2] it included 22,000 women in 400 medical centers in the United States and Canada.[3][4][5]

The study concluded that raloxifene caused fewer side-effects and less endometrial cancer than tamoxifen.[6][7] Raloxifene was found to be more effective at preventing noninvasive breast cancer but less effective at preventing invasive breast cancer.[8]

References

1. ^{{cite web | title=Study of Tamoxifen and Raloxifene (STAR) | publisher=Weill Cornell Medical College | url=http://www.cornellsurgery.org/patients/health/breast_star.html }}
2. ^"Osteoporosis drug equals tamoxifen in preventing breast cancer", Pittsburgh Post-Gazette, April 18, 2006
3. ^[https://www.nytimes.com/1999/06/16/us/drug-slashes-breast-cancer-risk-study-shows.html "Drug Slashes Breast Cancer Risk, Study Shows"], New York Times, June 16, 1999
4. ^{{cite web | author=Wickerham L | title=What is the Study of Tamoxifen and Raloxifene Breast Cancer Prevention Trial? | publisher=ABC News | url=http://abcnews.go.com/Health/OnCallPlusTreatment/study-tamoxifen-raloxifene-breast-cancer-prevention-trial/story?id=3656322#.Twxa5oE2yuI }}
5. ^{{cite web | title=Study of Tamoxifen and Raloxifene (STAR) | publisher=Columbia St. Mary's | url=http://www.columbia-stmarys.org/stw/Page.asp?PageID=STW037333 }}
6. ^{{cite web | title=Teleconference: Study of Tamoxifen and Raloxifene (STAR) P-2 | publisher=American Association for Cancer Research | url=http://aacrnews.wordpress.com/2010/04/19/teleconference-study-of-tamoxifen-and-raloxifene-star-p-2/ }}
7. ^[https://www.usatoday.com/news/health/2006-04-17-q-and-a-drug_x.htm "Raloxifene or tamoxifen: Which is the right drug for you?"], USA Today, April 17, 2006
8. ^"Raloxifene, Tamoxifen Both Guard Against Breast Cancer", Business Week, April 19, 2010

External links

  • [https://web.archive.org/web/20061213035327/http://www.cancer.gov/clinicaltrials/digestpage/STAR/page1 Study of Tamoxifen and Raloxifene (STAR) Trial]

2 : Breast cancer|Chemotherapy

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