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Synge is an Irish and British surname. Notable people with the name include: - Cathleen Synge (born 1923), Canadian mathematician a.k.a. Cathleen Synge Morawetz
- Edward Synge (archbishop of Tuam) (1659–1741), Anglican clergyman who served in the Church of Ireland
- Edward Synge (bishop of Elphin) (1691–1762), Anglican bishop in the Church of Ireland
- Edward Hutchinson Synge (1890–1957), inventor of the near-field optical microscope
- John Lighton Synge (1897–1995), Irish mathematician and physicist
- John Millington Synge (1871–1909), Irish playwright, poet, and prose writer
- Nicholas Synge (died 1771), 18th-century Irish Anglican priest
- Patrick Synge (1910–1982), British botanist, writer and plant hunter
- Richard Laurence Millington Synge (1914–1994), British biochemist
- Violet Synge Girl Guide Chief Commissioner for England
- William Synge (1826-1891), British diplomat and writer
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