| 词条 | Ternary complex |
| 释义 |
A ternary complex is a protein complex containing three different molecules that are bound together. In structural biology, ternary complex can also be used to describe a crystal containing a protein with two small molecules bound, for example cofactor and substrate; or a complex formed between two proteins and a single substrate.[1] In Immunology, ternary complex can refer to the MHC–peptide–T-cell-receptor complex formed when T cells recognize epitopes of an antigen. Some other example can be taken like ternary complex while eukaryotic translation, in which ternary complex is composed of eIF-3 & eIF-2 + Ribosome 40s subunit+ tRNAi. A ternary complex can be a complex formed between two substrate molecules and an enzyme. This is seen in multi-substrate enzyme-catalyzed reactions where two substrates and two products can be formed. The ternary complex is an intermediate between the product formation in this type of enzyme-catalyzed reactions. An example for a ternary complex is seen in random-order mechanism or a compulsory-order mechanism of enzyme catalysis for multi substrates. The term ternary complex can also refer to a polymer formed by electrostatic interactions.[2] References1. ^{{Cite book|title=Protein methyltransferases |first1=Steven G. |last1=Clarke |first2=Fuyuhiko |last2=Tamanoi |pages=162–172 |publisher=Academic Press|year=2006|isbn=978-0-12-122725-8}} 2. ^{{Cite book|title=Trends in colloid and interface science XVII |first1=Valérie |last1=Cabuil |first2=Pierre |last2=Levitz |first3=Clande |last3=Treiner |publisher=Springer |page=45 |year=2004 |isbn=978-3-540-20073-4}} Trevor Palmer (Enzymes, 2nd edition) {{Chemistry-stub}}{{Biochemistry-stub}}{{Molecular-biology-stub}} 1 : Protein complexes |
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