| 词条 | Tetrachlorodecaoxide |
| 释义 |
| Watchedfields = changed | verifiedrevid = 447812760 | IUPAC_name = Molecular oxygen tetrachlorite hydrate | image = | tradename = | routes_of_administration = | CAS_number_Ref = {{cascite|correct|??}} | CAS_number = 92047-76-2 | PubChem = 3000391 | ATC_prefix = D03 | ATC_suffix = AX11 }}Tetrachlorodecaoxide (TCDO) is a chlorite-containing, immunomodulatory, macrophage-activating drug whose chemical formula is Cl4H2O11.[1][2][3] The drug WF10 (Macrokine, Immunokine) is an aqueous solution of tetrachlorodecaoxide designed for intravenous injection.[2] Tetrachlorodecaoxide and WF10 were originally developed by Oxo Chemie.[4] Tetrachlorodecaoxide / WF10 is used in the management of radiation cystitis,[5] is effective in the treatment of diabetic foot ulcers,[6] and is used in wound healing, where the mechanism of action is activation of the macrophage system, and increasing the partial pressure of oxygen in the wound.[7] References1. ^{{cite web|url=https://pubchem.ncbi.nlm.nih.gov/compound/Tetrachlorodecaoxide|title=Tetrachlorodecaoxide - Cl4H2O11-4 |website=Pubchem.ncbi.nlm.mih.gov|accessdate=2016-12-20}} 2. ^1 {{cite web|url=http://drugprofiles.informa.com/drug_profiles/16509-wf10|title=WF10 |website=Drugprofiles.informa.com|accessdate=2016-12-20}} 3. ^{{cite journal |doi=10.1016/j.jcte.2016.05.001 |title=The chlorite-based drug WF10 constantly reduces hemoglobin A1c values and improves glucose control in diabetes patients with severe foot syndrome |journal=Journal of Clinical & Translational Endocrinology |volume=4 |pages=53–8 |year=2016 |last1=Maraprygsavan |first1=Paiboon |last2=Mongkolsuk |first2=Jarasporn |last3=Arnhold |first3=Juergen |last4=Kuehne |first4=Friedrich-Wilhelm }} 4. ^{{cite web|url=http://oxothai.com/about-us/|title=About Us - Immunokine® - WF10 - OXO Chemie (Thailand) Co., Ltd|website=Oxothai.com|accessdate=2016-12-20}} 5. ^{{cite journal |doi=10.1038/nrurol.2010.23 |pmid=20212517 |title=Management of radiation cystitis |journal=Nature Reviews Urology |volume=7 |issue=4 |pages=206–14 |year=2010 |last1=Smit |first1=Shaun G. |last2=Heyns |first2=Chris F. }} 6. ^{{cite journal |doi=10.12968/jowc.2013.22.3.130 |pmid=23665731 |title=Clinical outcomes of WF10 adjunct to standard treatment of diabetic foot ulcers |journal=Journal of Wound Care |volume=22 |issue=3 |pages=130–2, 134–6 |year=2013 |last1=Yingsakmongkol |first1=N. }} 7. ^{{cite journal |doi=10.5999/aps.2016.43.5.395 |pmid=27689045 |pmc=5040840 |title=The Efficacy and Safety of Tetrachlorodecaoxide in Comparison with Super-oxidised Solution in Wound Healing |journal=Archives of Plastic Surgery |volume=43 |issue=5 |pages=395–401 |year=2016 |last1=Parikh |first1=Romil |last2=Bakhshi |first2=Girish |last3=Naik |first3=Madhushree |last4=Gaikwad |first4=Bhargav |last5=Jadhav |first5=Kavita |last6=Tayade |first6=Mukund }} External links
2 : Chlorites|Immunomodulating drugs |
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