Thistle Brook may refer to:

• Thistle Brook, Buckinghamshire
• Thistle Brook, a river in the fictional Middle-earth

• Seediq (disambiguation)
• Seed-lending library
• Seedless Clothing Co.
• Seedless (fruit)
• Seedless grape
• Seed libraries
• Seed library
• Seedling mile
• Seedlings (film)
• Seed Macrobiotic Restaurant
• Seedman, Albert A.
• Seedmilk
• Seed milk
• Seed monopolies
• Seed of Destruction (Space: 1999)
• Seed oils
• Seedorf Castle
• Seed People
• Seedpeople
• Seed Plants
• Seed player
• Seed predators
• Seedral
• Seed (randomness)
• Seedrian