| 词条 | Tinyatoxin |
| 释义 |
| Watchedfields = changed | verifiedrevid = 421304832 | Name = Tinyatoxin | ImageFile = Tinyatoxin.svg | ImageSize = 200px | ImageName = | IUPACName = | Section1 = {{Chembox Identifiers | CASNo_Ref = {{cascite|correct|??}} | CASNo = 58821-95-7 | PubChem = 442098 | ChemSpiderID = 32701427 | SMILES = C[C@@H]1C[C@]2([C@H]3[C@H]4[C@]1([C@@H]5C=C(C(=O)[C@]5(CC(=C4)COC(=O)Cc6ccc(cc6)O)O)C)O[C@](O3)(O2)Cc7ccccc7)C(=C)C | StdInChI = 1S/C36H38O8/c1-21(2)34-17-23(4)36-28(32(34)42-35(43-34,44-36)19-25-8-6-5-7-9-25)15-26(18-33(40)29(36)14-22(3)31(33)39)20-41-30(38)16-24-10-12-27(37)13-11-24/h5-15,23,28-29,32,37,40H,1,16-20H2,2-4H3/t23-,28+,29-,32-,33-,34-,35-,36-/m1/s1 | StdInChIKey = WWZMXEIBZCEIFB-ACAXUWNGSA-N | MeSHName = tinyatoxin }} | Section2 = {{Chembox Properties | C=36 | H=38 | O=8 | Density = }}{{Infobox pepper | image = Hottest-chili-rating.gif | heat = Above peak | scoville = 5,300,000,000 }}Tinyatoxin (TTX or TTN) is a highly irritant analog of resiniferatoxin and capsaicin. It occurs naturally in Euphorbia poissonii.[1] It is a neurotoxin and (like its analogs) acts via vanilloid receptors of sensory nerves.[2] Tinyatoxin has a potential for pharmaceutical uses similar to uses of capsaicin. Tinyatoxin is about one third as strong as resiniferatoxin but is still an ultrapotent analogue of capsaicin, with a heat intensity estimate of 300 to 350 times that of capsaicin.{{citation needed|date=November 2018}} References1. ^Euphorbia poissonii in BoDD – Botanical Dermatology Database {{Transient receptor potential channel modulators}}{{organic-compound-stub}}2. ^{{cite journal |author1=Szallasi, A. |author2=Blumberg, P.M. |lastauthoramp=yes | title = Characterization of vanilloid receptors in the dorsal horn of pig spinal cord | journal = Brain Res | volume = 547 | pages = 335–338 | year = 1991 | doi = 10.1016/0006-8993(91)90982-2 | pmid = 1884211 | issue = 2}} 6 : Plant toxins|Terpenes and terpenoids|Carboxylate esters|Orthoesters|Ion channel toxins|Benzyl compounds |
| 随便看 |
|
开放百科全书收录14589846条英语、德语、日语等多语种百科知识，基本涵盖了大多数领域的百科知识，是一部内容自由、开放的电子版国际百科全书。