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词条 Tioclomarol
释义

  1. References

{{Drugbox
| Watchedfields = changed
| verifiedrevid = 443323079
| IUPAC_name = 3-[3-(4-Chlorophenyl)-1-(5-chloro-2-thienyl)-3-hydroxypropyl]-2-hydroxy-4H-chromen-4-one
| image = Tioclomarol.svg
| tradename =
| pregnancy_AU =
| pregnancy_US =
| pregnancy_category =
| legal_AU =
| legal_CA =
| legal_UK =
| legal_US =
| legal_status =
| routes_of_administration =
| bioavailability =
| protein_bound =
| metabolism =
| elimination_half-life =
| excretion =
| CAS_number = 22619-35-8
| ATC_prefix = B01
| ATC_suffix = AA11
| PubChem = 72147
| DrugBank_Ref = {{drugbankcite|correct|drugbank}}
| DrugBank =
| UNII_Ref = {{fdacite|correct|FDA}}
| UNII = E5B7C16LFK
| KEGG_Ref = {{keggcite|correct|kegg}}
| KEGG = D07137
| ChemSpiderID = 11236578
| ChEMBL = 2105401
| C=22 | H=16 | Cl=2 | O=4 | S=1
| molecular_weight = 447.331 g/mol
| StdInChI = 1S/C22H16Cl2O4S/c23-13-7-5-12(6-8-13)16(25)11-15(18-9-10-19(24)29-18)20-21(26)14-3-1-2-4-17(14)28-22(20)27/h1-10,15-16,25-26H,11H2
| StdInChIKey = WRGOVNKNTPWHLZ-UHFFFAOYSA-N
| smiles = c1ccc2c(c1)c(c(c(=O)o2)C(CC(c3ccc(cc3)Cl)O)c4ccc(s4)Cl)O
}}

Tioclomarol is an anticoagulant of the 4-hydroxycoumarin vitamin K antagonist type. It is a second generation drug, used as a rodenticide that is effective for the control of rodents that are resistant to this class of drugs.

References

{{Antithrombotics}}{{blood-drug-stub}}

4 : Thiophenes|Chloroarenes|Coumarin drugs|Vitamin K antagonists

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