| 词条 | Tobamovirus internal ribosome entry site (IRES) |
| 释义 |
| Name = Tobamovirus internal ribosome entry site (IRES) | image = RF00225.jpg | width = | caption = Predicted secondary structure and sequence conservation of IRES_Tobamo | Symbol = IRES_Tobamo | AltSymbols = Tobamo_IRES | Rfam = RF00225 | miRBase = | miRBase_family = | RNA_type = Cis-reg; IRES | Tax_domain = Viruses | GO = {{GO|0043022}} | SO = {{SO|0000243}} | CAS_number = | EntrezGene = | HGNCid = | OMIM = | PDB = | RefSeq = | Chromosome = | Arm = | Band = | LocusSupplementaryData = }} The Tobamovirus internal ribosome entry site (IRES) is an element that allows cap and end-independent translation of mRNA in the host cell.[1] The IRES achieves this by mediating the internal initiation of translation by recruiting a ribosomal 43S pre-initiation complex directly to the initiation codon and eliminates the requirement for the eukaryotic initiation factor, eIF4F.[2] See also
References1. ^{{cite journal | last = Ivanov | first = PA |author2=Karpova OV |author3=Skulachev MV |author4=Tomashevskaya OL |author5=Rodionova NP |author6=Dorokhov YuL |author7=Atabekov JG | year = 1997 | title = A tobamovirus genome that contains an internal ribosome entry site functional in vitro | journal = Virology | volume = 232 | pages = 32–43 | pmid = 9185586 | doi = 10.1006/viro.1997.8525 | issue = 1}} 2. ^{{cite journal | last = Kolupaeva | first = VG |author2=Pestova TV |author3=Hellen CU | year = 2000 | title = Ribosomal binding to the internal ribosomal entry site of classical swine fever virus | journal = RNA | volume = 6 | pages = 1791–1807 | pmid = 11142379 | doi = 10.1017/S1355838200000662 | issue = 12 | pmc = 1370049}} External links
2 : Cis-regulatory RNA elements|Tobamovirus |
| 随便看 |
|
开放百科全书收录14589846条英语、德语、日语等多语种百科知识，基本涵盖了大多数领域的百科知识，是一部内容自由、开放的电子版国际百科全书。