| 词条 | Tombusvirus 3' UTR region IV |
| 释义 |
| Name = Tombusvirus 3' UTR region IV | image = RF00176.jpg | width = | caption = Predicted secondary structure and sequence conservation of Tombus_3_IV | Symbol = Tombus_3_IV | AltSymbols = | Rfam = RF00176 | miRBase = | miRBase_family = | RNA_type = Cis-reg | Tax_domain = Viruses | GO = | SO = {{SO|0000205}} | CAS_number = | EntrezGene = | HGNCid = | OMIM = | PDB = | RefSeq = | Chromosome = | Arm = | Band = | LocusSupplementaryData = }}Tombusvirus 3' UTR is an important cis-regulatory region of the Tombus virus genome.[1] Tomato bushy stunt virus is the prototype member of the family Tombusviridae. The genome of this virus is positive sense single stranded RNA. Replication occurs via a negative strand RNA intermediate. In addition to viral proteins p33 and the RNA-dependent RNA polymerase p92, and unknown host factors, conserved and structural regions within the 3'untranslated region (3'UTR) are important for regulating genome replication. This 3' structural element contains a pseudoknot.[1][2] Other non-coding RNA structures in Tombusvirus include the 5' UTR and an internal replication element.[3] References1. ^1 {{cite journal |vauthors=Fabian MR, Na H, Ray D, White KA | title = 3'-Terminal RNA secondary structures are important for accumulation of tomato bushy stunt virus DI RNAs | journal = Virology | volume = 313 | issue = 2 | pages = 567–80 | year = 2003 | pmid = 12954222 | doi =10.1016/S0042-6822(03)00349-0 }} 2. ^{{cite journal |vauthors=Pogany J, Fabian MR, White KA, Nagy PD | title = A replication silencer element in a plus-strand RNA virus | journal = EMBO J. | volume = 22 | issue = 20 | pages = 5602–11 | year = 2003 | pmid = 14532132 | doi = 10.1093/emboj/cdg523 | pmc = 213777}} 3. ^{{cite journal | last = Monkewich | first = S |author2=Lin HX |author3=Fabian MR |author4=Xu W |author5=Na H |author6=Ray D |author7=Chernysheva OA |author8=Nagy PD |author9=White KA | year = 2005 | title = The p92 Polymerase Coding Region Contains an Internal RNA Element Required at an Early Step in Tombusvirus Genome Replication | journal = J Virol | volume = 79 | pages = 4848–4858 | pmid = 15795270 | doi = 10.1128/JVI.79.8.4848-4858.2005 | issue = 8 | pmc = 1069561}} External links
2 : Cis-regulatory RNA elements|Tombusviridae |
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