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词条 TraJ 5' UTR
释义

  1. References

  2. External links

{{Infobox rfam
| Name = traJ 5' UTR
| image = RF00243.jpg
| width =
| caption = Predicted secondary structure and sequence conservation of traJ_5
| Symbol = traJ_5
| AltSymbols =
| Rfam = RF00243
| miRBase =
| miRBase_family =
| RNA_type = Cis-reg
| Tax_domain = Bacteria
| GO =
| SO = {{SO|0000204}}
| CAS_number =
| EntrezGene =
| HGNCid =
| OMIM =
| PDB =
| RefSeq =
| Chromosome =
| Arm =
| Band =
| LocusSupplementaryData =
}}

The traJ 5' UTR is a cis acting RNA element which is involved in regulating plasmid transfer in bacteria.

In conjugating bacteria the FinOP system regulates the transfer of F-like plasmids. The FinP gene encodes an antisense RNA product that is complementary to part of the 5' UTR of the traJ mRNA.[1] The traJ gene encodes a protein required for transcription from the major transfer promoter, pY. The FinO protein is essential for effective repression, acting by binding to FinP and protecting it from RNase E degradation.

References

1. ^{{cite journal | vauthors = Arthur DC, Ghetu AF, Gubbins MJ, Edwards RA, Frost LS, Glover JN | title = FinO is an RNA chaperone that facilitates sense-antisense RNA interactions | journal = EMBO J. | volume = 22 | issue = 23 | pages = 6346–55 | year = 2003 | pmid = 14633993 | doi = 10.1093/emboj/cdg607 | pmc = 291848 }}

External links

  • {{Rfam|id=RF00243|name=traJ 5' UTR}}
  • {{Rfam|id=RF00107|name=Finp}}
{{molecular-cell-biology-stub}}

1 : Cis-regulatory RNA elements

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