“Tramazoline”的意思、由来-开放百科全书

词条

Tramazoline

释义

Brand names
References

{{Expand German|Tramazolin|date=December 2017}}{{Drugbox
| Verifiedfields = changed
| Watchedfields = changed
| verifiedrevid = 457287903
| IUPAC_name = N-(5,6,7,8-tetrahydronaphthalen-1-yl)-4,5-dihydro-1H-imidazol-2-amine
| image = Tramazoline.svg
| width = 175
| tradename =
| Drugs.com = {{drugs.com|international|tramazoline}}
| pregnancy_AU =
| pregnancy_US =
| pregnancy_category =
| legal_AU =
| legal_CA =
| legal_UK =
| legal_US =
| legal_status =
| routes_of_administration =
| bioavailability =
| protein_bound =
| metabolism =
| elimination_half-life =
| excretion =
| CAS_number_Ref = {{cascite|changed|??}}
| CAS_number = 1082-57-1
| ATC_prefix = R01
| ATC_suffix = AA09
| PubChem = 5524
| DrugBank_Ref = {{drugbankcite|correct|drugbank}}
| DrugBank =
| UNII_Ref = {{fdacite|correct|FDA}}
| UNII = SLE31693IV
| ChEMBL_Ref = {{ebicite|changed|EBI}}
| ChEMBL = 32573
| KEGG_Ref = {{keggcite|changed|kegg}}
| KEGG = D08624
| ChemSpiderID_Ref = {{chemspidercite|changed|chemspider}}
| ChemSpiderID = 5323
| C=13 | H=17 | N=3
| molecular_weight = 215.294 g/mol
}}

Tramazoline is a chemical that is used in the form of tramazoline hydrochloride in nasal decongestant preparations.^[1] It is an α-adrenergic receptor agonist that inhibits secretion of nasal mucus.

It was patented in 1961 and came into medical use in 1962.^[2]

Brand names

Australia

Spray-Tish^[3]
Rhinaspray

Austria

Rhinorix

Belgium

Rhinospray

Czech Republic

Muconasal Plus

Germany

Biciron
Ellatun
Rhinospray

Italy

Rinogutt
Fexallegra® nasale (Tramazoline + Chlorpheniramine, 1 mg/ml + 3.55 mg/ml)

Romania

Muconasal Plus (older)
Muconasal (newer)

Russia

Adrianol (tramazoline + phenylephrine)
Lasolvan Rhino

Spain

Rhinospray

Slovakia

Muconasal Plus

Ukraine

Lasorin

References

1. ^{{cite web|author=Boehringer Ingelheim|title=Spray-Tish Consumer Information|url=http://www.mydr.com.au/medicines/cmis/spray-tish-nasal-spray|work=Consumer Medicines Information|publisher=MyDr.com.au|accessdate=16 April 2011}}
2. ^{{cite book |last1=Fischer |first1=Jnos |last2=Ganellin |first2=C. Robin |title=Analogue-based Drug Discovery |date=2006 |publisher=John Wiley & Sons |isbn=9783527607495 |page=552 |url=https://books.google.ca/books?id=FjKfqkaKkAAC&pg=PA552 |language=en}}
3. ^{{cite web|title=Spray-Tish|url=http://www.nps.org.au/search_by_medicine_name/cmi/spray-tish|work=Consumer Information|accessdate=16 April 2011}}

2 : Imidazolines|Tetralins

随便看

开放百科全书收录14589846条英语、德语、日语等多语种百科知识，基本涵盖了大多数领域的百科知识，是一部内容自由、开放的电子版国际百科全书。