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词条 Trans-2-enoyl-CoA reductase (NAD+)
释义

  1. References

{{enzyme
| Name = trans-2-enoyl-CoA reductase (NAD+)
| EC_number = 1.3.1.44
| CAS_number = 77649-64-0
| IUBMB_EC_number = 1/3/1/44
| GO_code = 0050343
| image =
| width =
| caption =
}}

In enzymology, a trans-2-enoyl-CoA reductase (NAD+) ({{EC number|1.3.1.44}}) is an enzyme that catalyzes the chemical reaction

trans-2,3-dehydroacyl-CoA + NADH + H+ acyl-CoA + NAD+

Thus, the three substrates of this enzyme are trans-didehydroacyl-CoA, NADH, and H+, whereas its two products are acyl-CoA and NAD+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is acyl-CoA:NAD+ trans-2-oxidoreductase. This enzyme is also called trans-2-enoyl-CoA reductase (NAD+). This enzyme participates in butanoate metabolism.

References

  • {{cite journal | vauthors = Inui H, Miyatake K, Nakano Y, Kitaoka S | location = Tokyo | title = Purification and some properties of short chain-length specific trans-2-enoyl-CoA reductase in mitochondria of Euglena gracilis | journal = J. Biochem. | volume = 100| pages = 995–1000 | pmid = 3102464 | issue = 4 | date=October 1986}}
{{CH-CH oxidoreductases}}{{Enzymes}}{{Portal bar|Molecular and Cellular Biology|border=no}}{{1.3-enzyme-stub}}

3 : EC 1.3.1|NADH-dependent enzymes|Enzymes of unknown structure

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