“Trans-cinnamate 2-monooxygenase”的意思、由来-开放百科全书

词条

Trans-cinnamate 2-monooxygenase

释义

References

{{enzyme
| Name = trans-cinnamate 2-monooxygenase
| EC_number = 1.14.13.14
| CAS_number = 53126-56-0
| IUBMB_EC_number = 1/14/13/14
| GO_code = 0050344
| image =
| width =
| caption =
}}

In enzymology, a trans-cinnamate 2-monooxygenase ({{EC number|1.14.13.14}}) is an enzyme that catalyzes the chemical reaction

trans-cinnamate + NADPH + H⁺ + O₂ 2-hydroxycinnamate + NADP⁺ + H₂O

The 4 substrates of this enzyme are trans-cinnamate, NADPH, H⁺, and O₂, whereas its 3 products are 2-hydroxycinnamate, NADP⁺, and H₂O.

This enzyme belongs to the family of oxidoreductases, specifically those acting on paired donors, with O2 as oxidant and incorporation or reduction of oxygen. The oxygen incorporated need not be derived from O2 with NADH or NADPH as one donor, and incorporation of one atom o oxygen into the other donor. The systematic name of this enzyme class is trans-cinnamate,NADPH:oxygen oxidoreductase (2-hydroxylating). Other names in common use include cinnamic acid 2-hydroxylase, cinnamate 2-monooxygenase, cinnamic 2-hydroxylase, cinnamate 2-hydroxylase, and trans-cinnamic acid 2-hydroxylase. This enzyme participates in phenylalanine metabolism and phenylpropanoid biosynthesis.

References

{{cite journal |vauthors=Gestetner B, Conn EE |author-link2=Eric Conn | date = 1974 | title = The 2-hydroxylation of trans-cinnamic acid by chloroplasts from Melilotus alba Desr | journal = Arch. Biochem. Biophys. | volume = 163 | pages = 617–24 | pmid = 4153528 | doi = 10.1016/0003-9861(74)90522-0 | issue = 2 }}

4 : EC 1.14.13|NADPH-dependent enzymes|Enzymes of unknown structure|Hydroxycinnamic acids metabolism

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