词条 | Trans-endocytosis |
释义 |
Trans-endocytosis also applies to molecules. For example, this process is involved when a part of the protein Notch is cleaved off and undergoes endocytosis into its neighboring cell.[3][4] Without Notch trans-endocytosis, there would be too many neurons in a developing embryo.[5] Trans-endocytosis is also involved in cell movement when the protein ephrin is bound by its receptor from a neighboring cell.[6] References1. ^{{Cite journal|author=Spacek J|author2=Harris K. |date=April 2004|title=Trans-endocytosis via spinules in adult rat hippocampus|journal=J. Neurosci.|volume=24|issue=17|pages=4233–4241|pmid=15115819|doi=10.1523/JNEUROSCI.0287-04.2004}} {{cell-biology-stub}}2. ^{{Cite journal|author=Lauterbach J|author2=Klein R. |date=November 2006|title=Release of full-length EphB2 receptors from hippocampal neurons to cocultured glial cells|journal=J. Neurosci.|volume=26|issue=45|pages=11575–11581|pmid=17093078|doi=10.1523/JNEUROSCI.2697-06.2006}} 3. ^{{Cite journal|author=Krämer H.|title=RIPping notch apart: a new role for endocytosis in signal transduction?|journal=Sci STKE|date=April 2000|volume=2000|issue=29|pages=1pe–1|pmid=11752592|doi=10.1126/stke.2000.29.pe1}} 4. ^{{Cite journal|author=Parks AL|author2=Klueg KM |author3=Stout JR |author4=Muskavitch MA. |date=April 2000|title=Ligand endocytosis drives receptor dissociation and activation in the Notch pathway|journal=Development|volume=127|issue=7|pages=1373–1385|pmid=10704384}} 5. ^{{Cite journal|author=Klueg KM|author2=Muskavitch MA. |date=October 1999|title=Ligand-receptor interactions and trans-endocytosis of Delta, Serrate and Notch: members of the Notch signalling pathway in Drosophila|journal=J Cell Sci|volume=112|issue=19|pages=3289–3297|pmid=10504334}} 6. ^{{Cite journal|author=Marston DJ|author2=Dickinson S |author3=Nobes CD. |date=October 2003|title=Rac-dependent trans-endocytosis of ephrinBs regulates Eph-ephrin contact repulsion|journal=Nat. Cell Biol.|volume=5|issue=10|pages=879–888|pmid=12973357|doi=10.1038/ncb1044}} 1 : Cellular processes |
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